22.418 makale bulundu

Derin beyin stimülasyonu artı en iyi tıbbi terapiye karşı gelişmiş Parkinson hastalığı için tek başına en iyi tıbbi terapi (PD SURG denemesi): randomize, açık etiketli bir deneme.

Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial.

Williams A, Gill S, Varma T, Jenkinson C, Quinn N, Mitchell R, Scott R, Ives N, Rick C, Daniels J, Patel S, Wheatley K, PD SURG Collaborative Group.

Lancet Neurol · 2010-04-29

DOI: 10.1016/s1474-4422(10)70093-4PMID: 20434403

Dopamin agonistleri ile yapılan ön tedavi, 6-OHDA lezyonlu sıçanda anormal istemsiz hareketleri etkilemeden L-dopa aracılı rotasyonları etkiler.

Pre-treatment with dopamine agonists influence L-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat.

Lane EL, Dunnett SB.

Behav Brain Res · 2010-04-29

DOI: 10.1016/j.bbr.2010.04.034PMID: 20434491

Yeni bir anti-parkinsonya ajanı zonisamidin farelerde MPTP'ye (1-metil-4-fenil-1,2,3,6-tetrahidropiridine) nörotoksisiteye karşı terapötik etkisi.

Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice.

Yokoyama H, Yano R, Kuroiwa H, Tsukada T, Uchida H, Kato H, Kasahara J, Araki T.

Metab Brain Dis · 2010-04-28

DOI: 10.1007/s11011-010-9191-0PMID: 20424905

Mesenkimal kök hücrelerin intravenöz uygulaması, farelerin parkinsonian modeli üzerinde terapötik etkiler uygular: stromal hücre kaynaklı faktör-1alfanın nöroprotektif etkilerine odaklanır.

Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha.

Wang F, Yasuhara T, Shingo T, Kameda M, Tajiri N, Yuan WJ, Kondo A, Kadota T, Baba T, Tayra JT, Kikuchi Y, Miyoshi Y, Date I.

BMC Neurosci · 2010-04-26

DOI: 10.1186/1471-2202-11-52PMID: 20420688

[Parkinson hastalığı olan hastalarda zihinsel bozuklukların tedavisi].

[Treatment of mental disorders in patients with Parkinson's disease].

Meincke U, Kosinski CM.

Fortschr Neurol Psychiatr · 2010-04-26

DOI: 10.1055/s-0029-1245307PMID: 20422492

Parkinson hastalığında farmakolojik tedavi: nöroproteksiyona odaklanın.

Pharmacological therapy in Parkinson's disease: focus on neuroprotection.

Kincses ZT, Vecsei L.

CNS Neurosci Ther · 2010-04-23

DOI: 10.1111/j.1755-5949.2010.00150.xPMID: 20438581

MPTP tedavisi substantia nigra reticulata nöronlarının bir alt kümesinde pre-pro-nociceptin / orphanin FQ mRNA ekspresyonunu arttırır.

MPTP treatment increases expression of pre-pro-nociceptin/orphanin FQ mRNA in a subset of substantia nigra reticulata neurons.

Gouty S, Brown JM, Rosenberger J, Cox BM.

Neuroscience · 2010-04-22

DOI: 10.1016/j.neuroscience.2010.04.033PMID: 20417255

BİFUNKSİYONEL/POLİFUNKSİYONEL DOPAMİN D2/D3 NEURODEJENERATİF HASTALIKLARININ TEDAVİSİ İÇİN NEUROPROTECTİF AJENLER

BIFUNCTIONAL/POLYFUNCTIONAL DOPAMINE D2/D3 AGONIST AS NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES

DUTTA ALOKE K.

· 2010-04-21

Granülosit koloni uyarıcı faktörle yapılan MPTP sonrası tedavi, Parkinson hastalığının fare modelinde nigrostriyal fonksiyonu iyileştirir.

Post-MPTP treatment with granulocyte colony-stimulating factor improves nigrostriatal function in the mouse model of Parkinson's disease.

McCollum M, Ma Z, Cohen E, Leon R, Tao R, Wu JY, Maharaj D, Wei J.

Mol Neurobiol · 2010-04-21

DOI: 10.1007/s12035-010-8118-4PMID: 20405343

Seçici Serotonin 2A / 2C Reseptör Nörodejeneratif Hastalıklar İçin Terapötik Olarak Ters Agonistler

Selective Serotonin 2A/2C Receptor Inverse Agonists as Therapeutics for Neurodegenerative Diseases

WEINER DAVID M, DAVIS ROBERT E, BRANN MARK R, ANDERSSON CARL-MAGNUS A, ULDAM ALLAN K.

· 2010-04-13

Seçici Serotonin 2A / 2C Reseptör Nörodejeneratif Hastalıklar İçin Terapötik Olarak Ters Agonistler

Selective Serotonin 2A/2C Receptor Inverse Agonists as Therapeutics for Neurodegenerative Diseases

WEINER DAVID M, DAVIS ROBERT E, BRANN MARK R, ANDERSSON CARL-MAGNUS A, ULDAM ALLAN K.

· 2010-04-13

AMYOTROPHIC LATERAL SCLEROSIS, RHEUMATOID ARTHRITIS, TREMERS/PARKINSON'S DIŞI, ÇOKLU DÜZELTME DÜZENLİ KANSERLER, ALZHEIMERLER'S HASTALIK, MUSCULAR DYSTROPHİSİ, ATSEKSİYON DEFİKATÖRÜSÜSÜ,

PROCESS FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS, RHEUMATOID ARTHRITIS, TREMORS/PARKINSON'S DISEASE, MULTIPLE SCLEROSIS, NON-VIRAL BASED CANCERS, ALZHEIMERS'S DISEASE, MUSCULAR DYSTROPHY, ATTENTION DEFICIT DISORDER, ATTENTION DEFICIT HYPERACTIVITY DISORDER, COMPLEX REGIONAL PAIN SYNDROME, DIABETES, NEUROPATHIC PAIN, SPIDER ARTHRITIS, WEST NILE VIRUS, FIBROMYALGIA, SHINGLES, GOUT, MIGRAINE HEADACHES, SENILE DEMENTIA, POST POLIO SYNDROME, CENTRAL VIRUS DEAFNESS, ASTHMA, CHRONIC PAIN OF UNKNOWN ORIGIN AND HEPATITIS C

NELSON GEORGE.

· 2010-04-13