3.111 makale bulundu

Gerçek dünya telefon görüşmelerinin büyük dil modeli analizi, parkinsonizmin prodromal ve ilerici biyobelirteçlerini ortaya koymaktadır: iki yıllık bir kavram kanıtı çalışması.

Large language model analysis of real-world phone calls reveals prodromal and progressive biomarker of parkinsonism: A two-year proof-of-concept study.

Šubert M, Illner V, Novotný M, Kouba T, Tykalová T, Šimek M, Sovka P, Švihlík J, Růžička E, Šonka K, Dušek P, Rusz J.

PLOS Digit Health · 2026-07-09

DOI: 10.1371/journal.pdig.0001458PMID: 42424241

Parkinson's disease focused multimodal wearable vision based gait monitoring system with real time feedback to support mobility and caregiver well-being.

M U A, K UR, N P, M K, S C N, Dharrao D, Bongale AM.

Discov Ment Health · 2026-07-09

DOI: 10.1007/s44192-026-00539-9PMID: 42426290

Serum aromatik l-amino asit dekarboksilaz aktivitesi, prodromal ve manifesto Parkinson hastalığı için bir biyobelirteç olarak.

Serum aromatic l-amino acid decarboxylase activity as a biomarker for prodromal and manifest Parkinson's disease.

Beckers M, Kersten I, Pavelka L, Kuiperij HB, Krüger R, Bloem BR, Verbeek MM.

EBioMedicine · 2026-07-09

DOI: 10.1016/j.ebiom.2026.106354PMID: 42424702

Genome-wide association studies identify genetic determinants of synucleinopathy biomarkers.

Somerville EN, Liu L, Ta M, Iwaki H, Senkevich K, Alcalay RN, Gan-Or Z.

· 2026-07-08

DOI: 10.21203/rs.3.rs-10165954/v1

Sahneye özgü dijital sağlık teknolojisi biyobelirteçleri Parkinson hastalığında tanı ve erken ilerleme tespitini geliştirir.

Stage-specific digital health technology biomarkers enhance diagnostic and early progression detection in Parkinson's disease.

Czech MD, Sawicki S, Zadikoff C, Liu C, Robieson W, Liu Y, Shi W, Shen J, Crouthamel M, Quinton MS, Cosman J, Dorsey ER, Adams JL, Nevler N.

Front Neurol · 2026-07-08

DOI: 10.3389/fneur.2026.1869945PMID: 42488389

Syntaxin-4 at the Crossroads of Synaptic Plasticity and Neurodegeneration: From Molecular Mechanisms to Biomarker and Therapeutic Potential.

Li Y, Wei Y, Zhao J, Quan P, Wang C, Jiang M.

CNS Neurol Disord Drug Targets · 2026-07-08

DOI: 10.2174/0118715273465885260623094946PMID: 42458952

Parkinson hastalığı ciddiyeti için uzunlamasına ses biyobelirteç yörünge modellemesi: mPower gerçek dünya akıllı telefon verileri üzerinde etki alanı-adaptif transfer öğrenme.

Longitudinal voice biomarker trajectory modelling for Parkinson's disease severity: domain-adaptive transfer learning on mPower real-world smartphone data.

Johnson DR, Logeswari G.

Front Digit Health · 2026-07-07

DOI: 10.3389/fdgth.2026.1864460PMID: 42483429

Substantia Nigra Imaging Biomarker Segmentation for Parkinson's Disease Diagnosis via Transformer-Enhanced U-Net Architecture.

Zhang Z, Guo Z, Singh J, Zhao F, Liu W, Liu H.

IEEE J Biomed Health Inform · 2026-07-07

DOI: 10.1109/jbhi.2026.3710889PMID: 42412660

3D OCT-Based Retinal Biomarker Analysis for Automatic Regional-Wise Characterization of Neurodegenerative Diseases.

Álvarez-Rodríguez L, Vázquez C, Cordón B, Garcia-Martin E, de Moura J, Novo J, Ortega M.

J Imaging Inform Med · 2026-07-07

DOI: 10.1007/s10278-026-02098-5PMID: 42414714

Actigraphy Meets AI: Parkinson Hastalığı ve İzole REM Uyku Davranış Bozukluğu için Dijital Bir Biyobelirteç.

Actigraphy Meets AI: A Digital Biomarker for Parkinson's Disease and Isolated REM Sleep Behaviour Disorder.

Lopes L, Warncke JD, Filchenko I, Shi K, Bassetti CLA, Schäfer C.

J Sleep Res · 2026-07-07

DOI: 10.1111/jsr.70396PMID: 42412000

Parkinson hastalığında laktat dinamikleri: striatal devre kırılganlığı, biyobelirteç potansiyeli ve terapötik pencereler.

Lactate dynamics in Parkinson's disease: striatal circuit vulnerability, biomarker potential, and therapeutic windows.

Kong J, Yang Z, Wang Y, Liu L, Liu Y, Chen W.

Mol Med · 2026-07-06

DOI: 10.1186/s10020-026-01551-zPMID: 42410540

Rapidly progressive dementia with parkinsonism in the Italian CJD Registry: underlying pathology and clinical-biomarker clues for differential diagnosis.

Costanzo M, Vaianella L, Poleggi A, Baiardi S, Bentivenga GM, Capellari S, Belvisi D, Sbriccoli M, Equestre M, Porreca F, Colaizzo E, Aiello F, Conte A, Fabbrini G, Colosimo C, Zanusso G, Berardelli A, Parchi P, Ladogana A, Tiple D.

Parkinsonism Relat Disord · 2026-07-06

DOI: 10.1016/j.parkreldis.2026.108413PMID: 42418872