14.182 makale bulundu

Aberrant accumulation of α-synuclein might be linked with the progressive motor deficits in a mouse model of Angelman syndrome

Das S, Giri B, Jana NR.

· 2026-09-03

DOI: 10.64898/2026.08.27.747679

From genes to pathways: genetic convergence in early-onset Parkinson’s disease in India

Menon R, Khan AI, Elangovan D, Kandadai RM, Goyal V, Desai SD, Joshi D, Kumar H, Wadia PM, Mukherjee A, Kumar N, Mehta S, Geetha TS, Chargulla S, Murugan S, Venkata M, Shah HS, Paramanandam V, Chandarana M, Yadav R, Dhamija RK, Pal PK, Biswas A, Gupta R, Borgohain R, Ramprasad V, Kukkle PL, Parkinson Research Alliance of India (PRAI).

· 2026-09-03

DOI: 10.64898/2026.08.31.26361762

Complementary biomarkers or conflicting signals? DaT SPECT and synuclein skin biopsy in parkinsonian syndromes.

Martinez-Nunez AE, Walker-Pizarro N, Wagle Shukla A, Ramirez-Zamora A, McFarland NR.

BMJ Neurol Open · 2026-09-03

DOI: 10.1136/bmjno-2026-001759PMID: 42707903

Early-onset parkinsonism as a presenting feature of suspected type 1 Gaucher disease with two pathogenic <i>GBA1</i> variants: a case report.

Sun Y, Ni R, Yu Y.

Front Neurosci · 2026-09-03

DOI: 10.3389/fnins.2026.1920271PMID: 42757141

Integrative Meta-GWAS of European and Multi-Ancestry Parkinson’s Disease Studies Refines Genetic Risk Architecture and Prioritizes Unresolved Candidate Loci

Khalique F, Nadia Sheikh F, Mustafa H.

· 2026-09-02

DOI: 10.20944/preprints202609.0155.v1

High frequency of LRRK2 p.Gly2019Ser in Moroccan Parkinson's disease: RFLP as a reliable genotyping approach.

El Bardai S, Aboulem G, Ahmadi Y, Errazouki L, Bouhda N, Samri I, Abbassi M, Kettani O, El Agy F, Chbani L, Messouak O, Bouguenouch L, Belahsen MF, Ouldim K.

Neurogenetics · 2026-09-02

DOI: 10.1007/s10048-026-00936-wPMID: 42684504

Exploring the genetic spectrum of parkinsonism in Brazil.

Ferreira MG, Tesson C, Courtin T, de Macedo GL, Tenório RB, Raskin S, Lesage S, Brice A, Teive HAG.

Parkinsonism Relat Disord · 2026-09-02

DOI: 10.1016/j.parkreldis.2026.108958PMID: 42691865

Dual effect of α-synuclein disease variants on condensate formation.

Chandran A, Agarwal A, Wang T, Amaral L, Chen S, Chaves SR, Outeiro TF, Lautenschläger J.

Nat Commun · 2026-09-02

DOI: 10.1038/s41467-026-77002-4PMID: 42823411

From optical control to translational readiness: an evidence-tiered framework for optogenetics in neuromuscular and neurological disorders.

Cao X, Liu Y, Ding M, Zhang C, Gao S, Chen H, Deng C.

Mater Today Bio · 2026-09-02

DOI: 10.1016/j.mtbio.2026.103643PMID: 42733868

Dopaminergic Degeneration and GBA Mutation Status Predict Prior–Sensory Arbitration Disruption in Parkinson's Disease: A Multimodal Computational Framework

Tran K.

· 2026-09-01

DOI: 10.21203/rs.3.rs-10864931/v1

Dysregulated splenic glucocorticoid sensitivity in aging and an α-synuclein transgenic mouse model of Parkinson’s disease

Rombach D, Bopp V, Langgartner D, Grozdanov V, Kassubek J, Touma C, Reber SO, Danzer KM.

· 2026-09-01

DOI: 10.64898/2026.08.27.745197

Nedensel zincirin genetik risk varyantlarından Parkinson hastalığında lipit dismetabolizmasına haritalanması.

Mapping the causal chain from genetic risk variants to lipid dysmetabolism in Parkinson's disease.

De-Paula RB, Kim J, Rhinn H, Saade H, Chavez F, Segura T, Lozano MV, Etoundi M, Silos K, Kass N, Korchina V, Doddapaneni H, Venner E, Masdeu JC, Pavlik V, Yu MM, Lin CR, Jankovic J, Buchman AS, Muzny D, Gibbs RA, Elsea SH, Abeliovich A, Lansbury P, Vanegas-Arroyave N, Shaw CA, Shulman JM.

Brain · 2026-09-01

DOI: 10.1093/brain/awag039PMID: 41627849