14.182 makale bulundu

Beyond Parkinson’s disease: expanding the neurodegenerative spectrum of GBA1- associated disorders

Feo F, Ramat S, Tramacere L, Govoni A, Caremani L, Grigioni G, Mei D, Falliano S, Marin F, Paoli A, Morrone A, Caciotti A.

· 2026-08-25

DOI: 10.21203/rs.3.rs-10567488/v1

Blood-Based α-Synuclein Seeding Activity: A Dual Plasma and Erythrocyte RT-QuIC Assay for the Enhanced Diagnosis and Clinical Staging of Multiple System Atrophy

Long X, Yi H, Wan L, Chen Z, Chen Y, Wang C, Peng L, Wu H, Chen D, Ouyang R, Li M, Jie Z, Gu Y, Du K, Zhang Z, Wang Y, Dong X, Wu X, Qiu R, Jiang H, Zou W.

· 2026-08-25

DOI: 10.21203/rs.3.rs-10754313/v1

Clinical utility of skin biopsy detection of phosphorylated alpha-synuclein in an outpatient practice.

Levine T, Freeman R, Murray N, Swanson A, Gibbons CT, Crowell J, Phillips J, Gibbons CH.

Front Neurol · 2026-08-25

DOI: 10.3389/fneur.2026.1868980PMID: 42712504

Motor System Neurodegeneration in Aging and Synucleinopathies: Circuit Vulnerability and Neuroimaging Biomarkers.

Wen J, Xu X, Ge Y.

Aging Dis · 2026-08-25

DOI: 10.14336/ad.2026.0457PMID: 42691220

LRRK2: Molecular Mechanisms in Parkinson's Disease.

Arias-Carrión O, Guerra-Crespo M, Ortuño-Sahagún D, Ortega-Robles E.

Int J Mol Sci · 2026-08-25

DOI: 10.3390/ijms27177606PMID: 42737506

Engineered α-Synuclein-specific nanobody CAR iTregs restrain neuroinflammation and proteinopathy in Parkinson’s disease mice

Calderoni A, Nannoni M, Ruffini G, Doglio M, Bercher Brayer C, Serena GS, Melki R, Casucci M, Bonini C, Muggeo S, Broccoli V.

· 2026-08-22

DOI: 10.64898/2026.08.21.746338

Divergent tau pathology profiles induced by distinct alpha-synuclein aggregates in non-human primates.

Darricau M, Neu-Faber C, Bourdenx M, Dovero S, Porras G, Thiolat ML, Trigo-Damas I, Garcia-Carrillo N, Herrero MT, Vila M, Obeso JA, Planche V, Bezard E, Dehay B.

Brain · 2026-08-22

DOI: 10.1093/brain/awag284PMID: 42631513

Quantifying the Acute Toxicity of Alpha-Synuclein Membrane-Accumulation in a Cell-Based Assay.

Li B, Anderson AK, Alnakhala H, Levy OA, Ramalingam N, Dettmer U.

J Mol Neurosci · 2026-08-22

DOI: 10.1007/s12031-026-02578-xPMID: 42631812

α-Synuclein impairs mitochondrial function and alters cryptochrome regulation in the substantia nigra

O’Sullivan SA, Kacperczyk-Perdyan A, Ulusoy A, Pinto-Costa R, Lee SS, Ławrynowicz U, Prehn J, Mieczkowski J, Di Monte DA.

· 2026-08-21

DOI: 10.64898/2026.08.18.745090

⁇ -Synüklein Formları Düşük İyonik Kuvvetlerde Belirgin Michelle-Like Meclisleri.

α-Synuclein Forms Distinct Micelle-Like Assemblies at Low Ionic Strengths.

Hertel S, Ray S, Saraceno F, Nisini G, Nasi G, Mason TO, Kunka A, Agrimaki E, Olesen DJ, Ruggeri FS, Buell AK.

Adv Sci (Weinh) · 2026-08-21

DOI: 10.1002/advs.77300PMID: 42627558

Glucocerebrosidase dysfunction in GBA1 carriers: insights from blood and macrophage analyses.

Nikolaev M, Kopytova A, Izyumchenko A, Senkevich K, Artynyuk A, Pidyurchina V, Baydakova G, Miliukhina I, Zakharova E, Emelyanov A, Pchelina S.

Mol Biol Rep · 2026-08-21

DOI: 10.1007/s11033-026-12610-3PMID: 42627573

Effects of α-Synuclein on the Lipid Phenotype of SZ95 Human Sebocytes: A Preliminary Study in the Context of Parkinson's Disease.

Mosca S, Bottillo G, Flori E, Kovacs D, Maiellaro M, Lozzi F, Cavallo A, Zouboulis CC, Simmini G, Luppino A, Novello C, Leta V, Gaudiano G, Devigili G, Eleopra R, Tagliavini F, Mazzetti S, Camera E, Cardinali G.

Cells · 2026-08-21

DOI: 10.3390/cells15161505PMID: 42645231