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A genome-wide cross-trait analysis reveals shared genetic architecture between essential tremor and Parkinson’s disease

Zhang L, Fan D, Zhuang Z, Wang W, Wu J, Si S, Zheng Y, Huang T.

· 2026-08-20

DOI: 10.21203/rs.3.rs-10671175/v1

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Bidirectional disruption of Lrrk2 function drives T cell dysregulation and an exhaustion-like immune response

Sharp RC, Wall SC, Follet JC, Deng IB, Farrer MJ.

· 2026-08-20

DOI: 10.64898/2026.08.16.745139

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Pathogenic GBA1 Variants and their Interaction with the Gut-Microbiota-Brain Axis in Parkinson's Disease.

Dainton-Howard H, Engen P, Lawrence K, Shaikh M, Abdel-Mohsen M, Green S, Naqib A, Joshi N, Villanueva M, Kirby A, Keshavarzian A, Goetz C.

Mov Disord · 2026-08-20

DOI: 10.1002/mds.70496PMID: 42621775

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Hyphenated Mass Spectrometry-Based Strategies for Characterizing Oligomers of α‑Synuclein in Parkinson's Disease.

Sadighi R, Istrati A, Karijodikoro S, Scheefhals G, Baerenfaenger M, Rijs AM.

ACS Cent Sci · 2026-08-20

DOI: 10.1021/acscentsci.6c00514PMID: 42799140

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Astragalin confers coordinated neuroprotection in Parkinson's disease models through modulation of neurotrophic, anti-inflammatory, and synuclein-related pathways.

Wang J, He JY, Huang Q, Ma HY, Cao MM, Qin XY, Hu Y, Lan R.

Free Radic Biol Med · 2026-08-20

DOI: 10.1016/j.freeradbiomed.2026.08.036PMID: 42624301

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Silent Spread: Olfactory Bulb α-Synuclein Seeding in Wild-Type Mice Drives Pathology and Transient Neuroinflammation While Sparing Function

Anthonissen A, Iordache D, Vincent N, Elst WVD, Drinkenburg W, Verstreken P, Pita-Almenar JD, Maurin H, Ahnaou A.

· 2026-08-19

DOI: 10.21203/rs.3.rs-10656575/v1

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Neuronal overexpression of Kcnn1 in A53T α-synuclein mice suppresses phospho-serine 129 α-synuclein formation and doubles survival time.

Nagy M, Fenton WA, Horwich AL.

Proc Natl Acad Sci U S A · 2026-08-19

DOI: 10.1073/pnas.2622262123PMID: 42616775

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Genetic context unmasks olfactory loss as a marker for dyskinesia risk via levodopa exposure trajectories in Parkinson's disease.

Zhang Z, Zhan M, Zhao J, Wang Y.

Parkinsonism Relat Disord · 2026-08-18

DOI: 10.1016/j.parkreldis.2026.108942PMID: 42727510

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Crosstalk between α-synuclein accumulation, NLRP3 inflammasome activation, oxidative stress, and apoptosis in a rotenone-induced Parkinson rat model.

Pour HV, Alfateh M, Shanjani SM, Tajeri M, Abbasi-Maleki S.

Biochem Biophys Res Commun · 2026-08-18

DOI: 10.1016/j.bbrc.2026.154459PMID: 42628329

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Selective Neuronal Vulnerability to Alpha-Synuclein Pathology in Parkinson's Disease: A Critical Review of Mechanistic Rationale and Biomarker Stratification.

Livinț-Popa L, Nicolaie A, Mastaleru A, Socolov Ș, Mitrea M, Popescu G, Schreiner TG, Covali R, Cucu LE, Dima-Cozma LC, Cozma RS, Ciubotaru A, Olariu R, Ciurumelea CM, Borza LR, Vamanu A.

Med Sci (Basel) · 2026-08-17

DOI: 10.3390/medsci14040489PMID: 42646623

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Pathological α-synuclein propagation via the gut-liver axis induces liver injury in gut-origin Parkinson's disease mouse models.

Hu R, Wu J, Song YZ, Tao Y, Tan LL, Ma XY, Xia YM, Nie X, Li T, Li MA, Yao L, Huang SB, Jia XB, Qiao CM, Zhao WJ, Cui C, Shen YQ.

Exp Neurol · 2026-08-17

DOI: 10.1016/j.expneurol.2026.115965PMID: 42607920

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Optogenetic Control of cAMP Levels and HCN Channels: Implications in Cardiac Physiology and Parkinson’s Disease

Yang R, Wang D, Liu D, Liu P, Li S, Kang J.

· 2026-08-15

DOI: 10.64898/2026.08.13.744738

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Kayıtlar bilimsel kaynaklardan alınır. Bibliyografik kayıt sayısı, Türkçe çeviri veya editoryal onay sayısı değildir.

14.182 makale bulundu

A genome-wide cross-trait analysis reveals shared genetic architecture between essential tremor and Parkinson’s disease

Bidirectional disruption of Lrrk2 function drives T cell dysregulation and an exhaustion-like immune response

Pathogenic GBA1 Variants and their Interaction with the Gut-Microbiota-Brain Axis in Parkinson's Disease.

Hyphenated Mass Spectrometry-Based Strategies for Characterizing Oligomers of α‑Synuclein in Parkinson's Disease.

Astragalin confers coordinated neuroprotection in Parkinson's disease models through modulation of neurotrophic, anti-inflammatory, and synuclein-related pathways.

Silent Spread: Olfactory Bulb α-Synuclein Seeding in Wild-Type Mice Drives Pathology and Transient Neuroinflammation While Sparing Function

Neuronal overexpression of Kcnn1 in A53T α-synuclein mice suppresses phospho-serine 129 α-synuclein formation and doubles survival time.

Genetic context unmasks olfactory loss as a marker for dyskinesia risk via levodopa exposure trajectories in Parkinson's disease.

Crosstalk between α-synuclein accumulation, NLRP3 inflammasome activation, oxidative stress, and apoptosis in a rotenone-induced Parkinson rat model.

Selective Neuronal Vulnerability to Alpha-Synuclein Pathology in Parkinson's Disease: A Critical Review of Mechanistic Rationale and Biomarker Stratification.

Pathological α-synuclein propagation via the gut-liver axis induces liver injury in gut-origin Parkinson's disease mouse models.

Optogenetic Control of cAMP Levels and HCN Channels: Implications in Cardiac Physiology and Parkinson’s Disease

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