14.182 makale bulundu

Type 2 α-Synuclein Seed Amplification as a Diagnostic Reassessment Signal in Parkinson's Progression Markers Initiative Parkinson's Disease.

Yusufujiang A, Zeng S, Li H.

Mov Disord · 2026-08-06

DOI: 10.1002/mds.70471PMID: 42563488

Antemortem α-Synuclein levels from neuron-derived extracellular vesicles identify Lewy Body pathology in Parkinson’s Disease and Alzheimer Disease

Gunasekaran TI, Reyes-Dumeyer D, Gu Y, Volpert O, Beauregard D, Albers L, Teich A, Honig LS, Mayeux R, Eitan E, Vardarajan BN.

· 2026-08-05

DOI: 10.64898/2026.08.03.26359636

Alfa-sinüklein transgenik farelerde yüksek yağlı bir diyete epigenetik adaptasyon kaybı.

Loss of epigenetic adaptation to a high-fat diet in alpha-synuclein transgenic mice.

Hoof V, Schaffner SL, Dever K, MacIsaac J, Rotermund C, Kobor MS, Kahle PJ, Hentrich T, Schulze-Hentrich JM.

Front Cell Neurosci · 2026-08-05

DOI: 10.3389/fncel.2026.1901103PMID: 42620320

Rare Heterozygous Loss-of-Function Variants in MCOLN1 Identified in Two Sporadic Patients with α-Synucleinopathies.

Ying C, Chen X, Cen Z, Feng X, Jin N, Li J, Wang X, Luo W.

Mov Disord · 2026-08-05

DOI: 10.1002/mds.70469PMID: 42557761

QSAR-Guided Sanal Tarama ve Moleküler Dinamikler, Olaparib'i alfa-Synüklein Toplamasına Karşı Yeniden Tasarlayan Bir Kurşun Olarak Gösteriyor.

QSAR-Guided Virtual Screening and Molecular Dynamics Reveal Olaparib as a Repurposing Lead Against α-Synuclein Aggregation.

Abdelsayed M, Boulaamane Y.

Int J Mol Sci · 2026-08-05

DOI: 10.3390/ijms27157025PMID: 42589677

Terbutaline selectively reduces non-fibrillar α-synuclein aggregates and oxidative stress without affecting liquid-liquid phase separation or fibrillogenesis.

Biswas S, Mavlankar NA, Pal A, Roy I.

Eur J Pharmacol · 2026-08-05

DOI: 10.1016/j.ejphar.2026.179194PMID: 42556635

Tamamlayıcı Mitokondrial ve ⁇ -Synüklein İmzaları Parkinson Hastalığının Biyolojik Stratifikasyonunu Artırır.

Complementary Mitochondrial and α-Synuclein Signatures Refine Biological Stratification of Parkinson's Disease.

Fitzgerald JC, May P, Grünewald A.

Mov Disord · 2026-08-04

DOI: 10.1002/mds.70437PMID: 42548289

Reply to: Complementary Mitochondrial and α-Synuclein Signatures Refine Biological Stratification of Parkinson's Disease.

Percetti M, Yahya V, Fonzo AD, Monfrini E.

Mov Disord · 2026-08-04

DOI: 10.1002/mds.70436PMID: 42549513

All of Us araştırma programı veritabanındaki LRRK2 G2019S taşıyıcılarının analizi

Analysis of LRRK2 G2019S carriers in the All of Us research program database

Zimprich A.

· 2026-08-03

DOI: 10.21203/rs.3.rs-10550988/v1

Epilepsy-Dyskinesia Syndromes: The Venn Diagram of Genetic Epilepsy and Movement Disorders.

Bernardi K, Alecu JE, Achkar CME, Tochen L, Pearl PL, Ebrahimi-Fakhari D.

Mov Disord · 2026-08-03

DOI: 10.1002/mds.70403PMID: 42544821

Mechanistic insights into the inhibition of α-synuclein aggregation by sugar-based nanoparticles.

Alam D, Khan T, Sadiq I, Mudad P, Javed MA, Ahmad T, Islam A, Sardar M.

Biochim Biophys Acta Proteins Proteom · 2026-08-02

DOI: 10.1016/j.bbapap.2026.141168PMID: 42543145

⁇ -sinüklein fibrillerinde konformasyonel epitopları taklit eden aşılar Parkinson hastalığına bağışıklık sağlar.

Vaccines mimicking conformational epitopes on α-synuclein fibrils provide immunity to Parkinson's disease.

Ma L, Reithofer S, Pesch V, Flores-Fernandez JM, Sriraman A, Duckering C, Amidian S, Özdüzenciler P, Müller L, Wille H, Tamgüney G.

Brain · 2026-08-01

DOI: 10.1093/brain/awag010PMID: 41512110