Parkinson hastalığı olan ve lösin bakımından zengin tekrarlayan kinaz 2 gen mutasyonu taşıyan hastaların el esnekliğine çift görev müdahalesinin etkisi.

Araştırma özeti

Aşağıdaki metin kaynak makalenin lisansı doğrulanmış orijinal özetidir. cc by

The aim of the present study was to observe the changes in hand flexibility of patients with Parkinson's disease (PD) and the effect of dual-task interference. Patients with PD were distributed into two subgroups: the leucine-rich repeat kinase 2 (LRRK2) mutation PD (LRRK2+) and the LRRK2 mutation-free (LRRK2-) PD groups. The healthy controls were distributed into two subgroups: the LRRK2+ control and the LRRK2- control groups. The first task was the Purdue pegboard test. The second task was to perform serial seven subtractions. Single-task and dual-task tests were performed, respectively. The numbers of pegs inserted with the dominant hand, non-dominant hand and both hands in the pegboard test and the number of correct responses in the serial seven subtractions test within 30 sec were recorded. The United Parkinson's Disease Rating Scale (UPDRS) III score of examinees in the LRRK2+ PD group was significantly higher than that of examinees in the LRRK2- PD group (P+ PD group.

İlgili konular