Parkinson Hastalığı İlerlemesinde Diyet ve Beslenme Takviyelerinin Rolü.

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ObjectivesThe goal of this study is to describe modifiable lifestyle variables associated with reduced rate of Parkinson's disease (PD) progression.MethodsThe patient-reported outcomes in PD (PRO-PD) were used as the primary outcome measure, and a food frequency questionnaire (FFQ) was used to assess dietary intake. In this cross-sectional analysis, regression analysis was performed on baseline data to identify the nutritional and pharmacological interventions associated with the rate of PD progression. All analyses were adjusted for age, gender, and years since diagnosis.Results1053 individuals with self-reported idiopathic PD were available for analysis. Foods associated with the reduced rate of PD progression included fresh vegetables, fresh fruit, nuts and seeds, nonfried fish, olive oil, wine, coconut oil, fresh herbs, and spices (P P P = 0.026 and P = 0.019, resp.), and iron supplementation was associated with faster progression (P = 0.022).DiscussionThese are the first data to provide evidence that targeted nutrition is associated with the rate of PD progression.

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