Parkinson hastalığı olan hastalarda serbest yaşam koşulları altında invazif olmayan yürüyüş kaydının analizi: küresel bilişsel işlev ve motor anormalliklerle ilişki.

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BackgroundWe investigated the gait characteristics of patients with Parkinson's disease (PD), under free-living conditions, using a wearable device, and assessed their relationships with global cognitive function and motor abnormalities.MethodsThe study subjects comprised patients with PD aged ResultsThe study included 106 consecutive patients with PD. The mean gait cycle duration was 1.18 ± 0.12 s, which was similar to that of the normal controls. However, the mean gait acceleration amplitude of PD patients (1.83 ± 0.36 m/s2) was significantly lower than that of the control (p ConclusionsThe gait rhythm of PD patients is preserved at levels similar to those of normal subjects. However, the mean gait acceleration amplitude was significantly reduced in patients with PD. The results indicate that gait acceleration amplitude correlates with the severity of motor disorders and global cognitive function.

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