Parkinson hastalığında uyku bozuklukları üzerine Yijinjing'den ilham alan egzersizlerin etkinliği: kontrollü bir fNIRS çalışması.

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BackgroundSleep disorders are prevalent in Parkinson's disease (PD) patients, significantly impacting their quality of life and rehabilitation outcomes. This controlled trial aimed to investigate the impact of Yijinjing-inspired exercises on sleep disorders in PD patients, utilizing functional near-infrared spectroscopy (fNIRS) to assess neurophysiological changes.MethodsNinety-six PD patients were allocated to control, exercise, or music therapy groups for eight weeks. The Pittsburgh Sleep Quality Index (PSQI), along with the Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Unified Parkinson's Disease Rating Scale (UPDRS), and Parkinson's Disease Questionnaire (PDQ-39) were used to assess outcomes. fNIRS measured neurophysiological changes post-intervention.ResultsThe exercise group demonstrated substantial improvement in sleep quality after Bonferroni correction (PSQI: mean Δ = -1.78 ± 0.99, P P = 0.001 after Bonferroni adjustment, Cohen's d = 0.87), but not versus music therapy (P = 0.018 > 0.0167). fNIRS confirmed cortical reorganization in dorsolateral prefrontal cortex (Brodmann Area 9; Channel 3) and primary motor cortex (Brodmann Area 4; Channel 9) at FDR-corrected P P > 0.01).DiscussionYijinjing training may improve sleep quality in Parkinson's disease patients, with preliminary evidence of neuroplastic adaptation. Consideration could be given to exploring its integration into comprehensive rehabilitation approaches.

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