Serebral dopamin nörotrofik faktörünün (CDNF) C-domain'i, endoplazmik retikulum stres koşulları altında plazma zarına taşınan KDEL reseptörüne bağlanarak kardiyoprotektif aktivitesinden sorumludur.

The C-domain of the cerebral dopamine neurotrophic factor (CDNF) is responsible for its cardioprotective activity by binding to the KDEL receptor relocated to the plasma membrane under endoplasmic reticulum stress conditions.

de Oliveira DF, Maciel L, Dos Santos Silva A, Da Coutinho KC, Palhano FL, Santiago MF, Foguel D.

J Mol Cell Cardiol · 2026-01-24

DOI: 10.1016/j.yjmcc.2025.12.013PMID: 41587634