Parkinson Hastalığında Klinik Bakım İçin Uyku Kalitesinin İlişkisi: İyi ve Kötü Uyuyanlar Arasındaki Klinik ve Bilişsel Farklar: Kesitsel Bir Çalışma.

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Background/Objectives: This study aimed to compare disease severity and cognitive performance between Parkinson's disease (PD) patients with good and poor sleep quality. Methods: This cross-sectional observational study included 69 patients with PD. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Participants were classified as having good sleep quality (PSQI ≤ 5; n = 32) or poor sleep quality (PSQI > 5; n = 37). Disease severity was evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS) and Modified Hoehn and Yahr Scale (mH&Y). Global cognition, executive functions, and visuospatial performance were assessed using the Montreal Cognitive Assessment (MoCA), Stroop Test TBAG Form, and Clock Drawing Test, respectively. Results: Patients with poor sleep quality had significantly higher UPDRS scores (p = 0.004), longer disease duration (p = 0.043), and more advanced mH&Y (p p = 0.039) and lower Clock Drawing Test scores (p = 0.019). In addition, completion times on all Stroop test cards were significantly longer in the poor sleep quality group (p = 0.011-0.042), indicating poorer attention-executive performance. Moderate effect sizes were observed for disease severity and cognitive outcomes. Conclusions: Poor sleep quality was associated with greater disease severity and lower cognitive performance in early-to-mid-stage PD patients who were largely cognitively preserved. Routine assessment of subjective sleep quality may help identify patients with a higher clinical and cognitive burden and support more individualized, person-centered healthcare strategies in PD.

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