Sitokrom P4502D ve -2C enzimleri, fare karaciğeri mikrozomlarında parkinsonizm indükleyici maddenin 1-metil-4-fenil-1,2,3,6-tetrahidropiridinin oksidatif N-demetilasyonunu katalize eder.

Cytochrome P4502D and -2C enzymes catalyze the oxidative N-demethylation of the parkinsonism-inducing substance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rat liver microsomes.

Narimatsu S, Tachibana M, Masubuchi Y, Suzuki T.

Chem Res Toxicol · 1996-01-01

DOI: 10.1021/tx9500540PMID: 8924622