Kısa uyaran sunumu kullanan yeni psikofiziksel çizgi kesit görevi, sol başlangıçlı Parkinson Hastalığında yatay bir önyargı ortaya çıkarmadığını ortaya koyuyor

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Abstract Objective Some studies have shown that individuals with Parkinson’s disease (PD) with motor-symptom onset on the left side of the body (LPD) show mild neglect-like performance on some tasks, but others have not. Individuals with PD onset on the right side of the body (RPD) have not shown these effects. To clarify whether a bias in the perception of length exists in LPD, we administered a novel line bisection experiment, using psychophysical methods to isolate perceptual biases. Methods Experiment 1 used a psychophysical procedure to test 21 LPD, 29 RPD and 28 age-matched healthy control adults (HC) on horizontal line bisection. A vertical line bisection condition was included as a control. Experiment 2 repeated the horizontal condition in a subset of participants, using eye-tracking and a fixation cross to preclude gaze bias. Results In both experiments, LPD did not demonstrate performance bias that was consistent with hemineglect. In Experiment one, a bias specific to LPD was demonstrated in the vertical condition. Conclusions The present results suggest that any neglect-like perceptual shifts occurring in LPD do not occur when psychophysically isolating perceptual decisions from higher-order processes that may be at play in other tasks.

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