Parkinson hastalığında tıkanmış bozukluklar: Boyuna değişiklikler

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Background: Acquired neurogenic stuttering occurs in approximately 1 in 5 people with Parkinson’s disease. It is currently unknown how stuttering changes as the disease progresses. Objective: Examine longitudinal changes in the frequency of stuttered disfluencies in individuals with Parkinson’s disease. Method: We measured stuttered disfluencies in 63 people with Parkinson’s disease in conversation, picture description, and reading samples. All participants completed at least two assessment sessions, a mean of 2.9 years (± 1.5) apart. Nineteen completed a third session, and two a fourth. Bayesian hierarchical models were fitted to examine changes in the frequency of stuttered syllables over time for each speech task, accounting for baseline demographic (age, sex) and disease-associated variables (symptom duration, motor functioning, cognition, and medication dosage). Results: At baseline, the mean frequency of stuttered syllables was 2.1% (±1.4) during conversation, 1.4% (±1.4) during picture description, and 0.6% (±0.8) during reading. At baseline, 18% of participants exceeded a ≥3% stuttered disfluencies threshold for stuttering identification, while 38% met this threshold during follow up sessions. The group-level statistical models estimated an annual increase in stuttered disfluencies of 0.1% (95%CI [+0.0, 0.2]) for conversation and 0.2% (95%CI [+0.0, 0.3]) for picture description, but no increase for reading. Conclusion: Group-level analyses indicated a small but progressive increase in stuttered disfluencies over time in individuals with Parkinson’s disease. A subgroup of individuals showed more pronounced increases, exceeding a diagnostic threshold for stuttering. These findings highlight the importance of longitudinal monitoring to enable timely, targeted intervention for those impacted by speech disfluencies.

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