Orta Yaşamda Açlık Plazma Glikoz Çeşitlenebilirliği ve Parkinson Hastalığı Riski: Ulus Çapında Nüfusa Dayalı Bir Çalışma

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Abstract Background — Athough an association exists between type 2 diabetes and Parkinson’s disease (PD), the implications of glycemic variability on PD are unknown. We assessed the future risk of incident PD according to visit-to-visit fasting plasma glucose (FPG) variability; this was calculated using standard deviation (FPG-SD), coefficient variance (FPG-CV), and variability independent of the mean (FPG-VIM). Methods — Using the Korean National Health Insurance Service–Health Screening Cohort, we followed 131,625 Korean adults without diabetes. This study population was divided into a midlife group (

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