14.936 articles found

LRRK2 kinase modulates glucose-stimulated insulin secretion via RAB8 phosphorylation and ciliogenesis

Dule N, Marku A, Galli A, Pischedda F, Lama A, Castagna M, Marciani P, Bertuzzi F, Piccoli G, Perego C.

Cell. Mol. Life Sci · 2025-12-01

Multi‐scale imaging of α‐synuclein, dopamingeric neurodegeneration and microstructural changes in α‐synuclein PFF mouse model of Parkinson's disease

Combes B, Rosenau A, Huang S, Karatsoli M, Reisert M, Chen Y, Yoshihara H, Keller A, von Elverfeldt D, Jakab A, Oertel W, Nitsch R, Geibl F, Razansky D, Henrich M, Hock C, Ni R.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

Mthfr deficiency and SARS‐CoV‐2 infection synergistically deplete dopamine and upregulate α‐synuclein increasing the risk of Parkinson's disease

Umar M, Ismael S, Bix G.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

Genetic architecture of Parkinson's disease: investigating the relationships between pathway‐specific polygenic risk scores and neuroanatomical features

Azizi H, Pastor‐Bernier A, Tremblay C, Abbasi N, Liu L, Senkevich K, Pourmajidian M, Morys F, Savadjiev P, Yu E, Poline J, Gan‐Or Z, Zeighami Y, Dagher A.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

The Novel PET Radioligand [11C]MK‐7337 Detects Alpha‐Synuclein Pathology in Parkinson's Disease Patients

Yuchuan W, Mitchell H, Lee S, Zeng Z, Miller P, Bennacef I, Riffel K, Purcell M, Haley H, Gantert L, Marie H, Meng X, Stenslik M, Ma L, Fay J, Li W, Marcus J, Smith S, Uslaner J, Drolet R, Hostetler E.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

Inflammatory stress on induced neurons carrying Parkinson's disease‐associated LRRK2 Mutations

Torrellas J, Chairmandurai A, Mamais A, LaVoie M, Chakrabarty P.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

Synergistic Modulation of GTPase Hydrolysis and mTORC1 Activity in LRRK2-G2019S Parkinson’s Disease

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Innovation in aging · 2025-12-01

Glial interaction with Parkinsonian disorders biomarkers: alpha‐synuclein, dopaminergic dysfunction and clinical stages

Souza L, dos Santos D, Zimmer E, Borelli W, Schumacher‐Schuh A.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

Plasma Synuclein Aggregate Detection via Constant Shake‐Induced Conversion: A Novel Biomarker for Parkinson's Disease Diagnosis and Progression

Ryoo N, Ko H.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025-12-01

Interplay between lipid droplets and alpha-synuclein: implication in Parkinson's disease pathogenesis.

Idi W, Sheta R, Oueslati A.

Front Mol Neurosci · 2025-12-01

DOI: 10.3389/fnmol.2025.1681039PMID: 41404624

Tracking prodromal α-synucleinopathies: novel fluid- and tissue-based biomarker approaches for iRBD phenoconversion.

Bruschi G, Bortolin E, Mazzeo S, Bombaci A, Pozzi FE, Agosta F, Ferini-Strambi L, Filippi M, Salsone M.

Sleep · 2025-12-01

DOI: 10.1093/sleep/zsaf174PMID: 40578329

The influence of the glymphatic system on α-synuclein propagation: the role of aquaporin-4.

Lopes DM, Llewellyn SK, Bury SE, Wang J, Wells JA, Gegg ME, Verona G, Lythgoe MF, Harrison IF.

Brain · 2025-12-01

DOI: 10.1093/brain/awaf255PMID: 40632813