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DDOX expands the repertoire of tetracyclines for Parkinson's disease by preventing the cellular uptake and intracellular impact of α-synuclein preformed fibrils.

Teran MDM, Tomas-Grau RH, Soliz-Santander ES, Guayán ML, Budeguer Isa V, Luna Mercado A, Avila CL, Sosa-Padilla B, Cruz H, Ciss I, Besnault P, Socias SB, Vera Pingitore E, Ferrié L, Raisman-Vozari R, Michel PP, Figadère B, Chehín RN, Ploper D.

Sci Rep · 2025-10-29

DOI: 10.1038/s41598-025-15991-wPMID: 41162400

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Design, Synthesis and Evaluation of the First 2-Alkynyl(aza)indole <sup>18</sup>F Probe Targeting α-Synuclein Aggregates.

Boiaryna L, Pieri L, Chalon S, Serrière S, Bodard S, Chicheri G, Chenaf E, Suzenet F, Melki R, Buron F, Routier S, Vercouillie J.

Pharmaceuticals (Basel) · 2025-10-29

DOI: 10.3390/ph18111638PMID: 41304884

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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MPP<sup>+</sup> induces α-synuclein oligomerization and neurite impairment by disrupting mitochondrial function and Akt signaling, with apigenin emerging as a potential neuroprotective agent.

Reudhabibadh R, Champoochana N, Kuedo Z, Thammanichanon P, Hutamekalin P, Binlateh T.

Food Chem Toxicol · 2025-10-27

DOI: 10.1016/j.fct.2025.115821PMID: 41161370

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

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