15.814 articles found

Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.

Bayer TA, Jäkälä P, Hartmann T, Havas L, McLean C, Culvenor JG, Li QX, Masters CL, Falkai P, Beyreuther K.

Neurosci Lett · 1999-05-01

DOI: 10.1016/s0304-3940(99)00311-0PMID: 10465711

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation.

Narhi L, Wood SJ, Steavenson S, Jiang Y, Wu GM, Anafi D, Kaufman SA, Martin F, Sitney K, Denis P, Louis JC, Wypych J, Biere AL, Citron M.

J Biol Chem · 1999-04-01

DOI: 10.1074/jbc.274.14.9843PMID: 10092675

A large Japanese family with Machado-Joseph disease: clinical and genetic analysis.

Yoritaka A, Nakagawa-Hattori Y, Hattori N, Kitahara A, Mizuno Y.

Acta Neurol Scand · 1999-04-01

DOI: 10.1111/j.1600-0404.1999.tb07354.xPMID: 10225355

Extensive axonal Lewy neurites in Parkinson's disease: a novel pathological feature revealed by alpha-synuclein immunocytochemistry.

Braak H, Sandmann-Keil D, Gai W, Braak E.

Neurosci Lett · 1999-04-01

DOI: 10.1016/s0304-3940(99)00208-6PMID: 10327208

Genetics of Parkinson's disease.

Mizuno Y, Hattori N, Mori H.

Biomed Pharmacother · 1999-04-01

DOI: 10.1016/s0753-3322(99)80075-4PMID: 10349506

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease.

Abbas N, Lücking CB, Ricard S, Dürr A, Bonifati V, De Michele G, Bouley S, Vaughan JR, Gasser T, Marconi R, Broussolle E, Brefel-Courbon C, Harhangi BS, Oostra BA, Fabrizio E, Böhme GA, Pradier L, Wood NW, Filla A, Meco G, Denefle P, Agid Y, Brice A.

Hum Mol Genet · 1999-04-01

DOI: 10.1093/hmg/8.4.567PMID: 10072423

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro.

Hashimoto M, Hsu LJ, Xia Y, Takeda A, Sisk A, Sundsmo M, Masliah E.

Neuroreport · 1999-03-01

DOI: 10.1097/00001756-199903170-00011PMID: 10208537

Immunohistochemical and neurochemical studies on nigral and striatal functions in the circling (ci) rat, a genetic animal model with spontaneous rotational behavior.

Richter A, Ebert U, Nobrega JN, Vallbacka JJ, Fedrowitz M, Löscher W.

Neuroscience · 1999-03-01

DOI: 10.1016/s0306-4522(98)00321-2PMID: 10077328

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro.

Giasson BI, Uryu K, Trojanowski JQ, Lee VM.

J Biol Chem · 1999-03-01

DOI: 10.1074/jbc.274.12.7619PMID: 10075647

Synoretin--A new protein belonging to the synuclein family.

Surguchov A, Surgucheva I, Solessio E, Baehr W.

Mol Cell Neurosci · 1999-02-01

DOI: 10.1006/mcne.1999.0735PMID: 10192768

[Genetic dystonia].

Destée A, Brique S, Sablonnière B.

Presse Med · 1999-02-01

PMID: 10073176

Intracerebral transplantation of genetically engineered cells in a rat model of Parkinson's disease

Ljungberg MC.

· 1999-01-01