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Novel in situ seeding immunodetection assay uncovers neuronal-driven alpha-synuclein seeding in Parkinson's disease.

Otero-Jimenez M, Wojewska MJ, Jogaudaite S, Miller D, Gray-Rodriguez S, Geoghegan GC, Abelleira-Hervas L, Viney TJ, Sarkany B, Gveric D, Gentleman S, Alegre-Abarrategui J.

NPJ Parkinsons Dis · 2025-08-25

DOI: 10.1038/s41531-025-01111-yPMID: 40855085

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies.

An S, McInnis JJ, Kim D, Li Y, Tasdemir-Yilmaz O, Ahn J, Mackness BC, Kwon SH, Bonner JM, Yoo M, Dujardin S, Kim D, Park J, Yun H, Tang Y, Pradier L, Hyeon S, Song D, Sung B, Krishnan R, Spencer B, Rissman RA, Sandhu JK, Haqqani AS, Shin JW, Kim DB, Lee H, Jung J, You WK, Star AT, Delaney CE, Stanimirovic DB, Sardi SP, Lee SH, Kayatekin C.

NPJ Parkinsons Dis · 2025-08-22

DOI: 10.1038/s41531-025-01117-6PMID: 40847026

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

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