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Effects of α-synuclein pathology in normal aging and Alzheimer’s disease

Winer JR, Plastini MJ, Romero A, Vossler H, Sai I, Channappa D, Abdelnour C, Shahid-Besanti M, Wilson EN, Young CB, Trelle A, Yutsis M, Sha S, Ramirez V, Taylor R, Younes K, Wyss-Coray T, Henderson VW, Wagner AD, Poston KL, Mormino EC.

· 2025-08-08

DOI: 10.1101/2025.08.06.25333152

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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<i>LRRK2</i> p.G2385R and p.R1628P Variants in a Multi-Ethnic Asian Parkinson’s Cohort: Epidemiology and Clinical Insights

Goh JW, Lim JL, Ong RY, Yong QH, Lew CCY, Toh TS, Hor JW, Tay YW, Zulkefli J, Anuar ANK, Ding HX, Schee JP, Beh YY, Ibrahim KA, Mawardi AS, Lim TT, Looi I, Chia YK, Ooi JCE, Law WC, Wong SC, Lau YH, Teh PC, Ong TL, Cheah WK, Sammler E, Padmanabhan S, Lit LC, Tan EK, Ahmad-Annuar A, Lim S, Tan AH.

· 2025-08-08

DOI: 10.1101/2025.08.06.25332985

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Expression of human A53T alpha-synuclein without endogenous rat alpha-synuclein fails to elicit Parkinson's disease-related phenotypes in a novel humanized rat model.

Polinski NK, Puoliväli J, Rauhala L, Stenius TK, Bragge T, Parkkari T, Penttinen AM, Chen Y, Mabrouk OS, Glajch KE, Hirst WD, Perkinton M, Martinez TN, Frasier MA.

PLoS One · 2025-08-08

DOI: 10.1371/journal.pone.0329823PMID: 40779487

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Isobavachalcone inhibits α-synuclein fibrillogenesis and its Parkinson's disease variants, disassembles the mature fibrils and alleviates cellular toxicity.

Xie F, Zhu C, Sun L, Lin Q, Fang P, Li A, Lai T, Ma C, Zhang Y, Lu Y, Chen Y, Zhang Y, Xiao S, Yang X, Yin G, Lv G.

Int J Biol Macromol · 2025-08-07

DOI: 10.1016/j.ijbiomac.2025.146541PMID: 40763859

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Proteomic signatures of the <i>APOE ε4</i> and <i>APOE ε2</i> genetic variants and Alzheimer’s disease

Lu L, Pichet Binette A, Hristovska I, Janelidze S, Smets B, Cumplido Mayoral I, Vasanthakumar A, Milkovich B, Ossenkoppele R, Krish V, Imam F, Palmqvist S, Vogel J, Stomrud E, Hansson O, Mattsson-Carlgren N.

· 2025-08-06

DOI: 10.1101/2025.08.04.25332945

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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