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A novel allosteric GCase modulator prevents Tau accumulation in GBA1<sup>WT</sup> and GBA1<sup>L444P/L444P</sup> cellular models.

Ciccaldo M, Pérez-Carmona N, Piovesana E, Cano-Crespo S, Ruano A, Delgado A, Fregno I, Calvo-Flores Guzmán B, Bellotto M, Molinari M, Taylor J, Papin S, García-Collazo AM, Paganetti P.

Sci Rep · 2025-05-21

DOI: 10.1038/s41598-025-02346-8PMID: 40399377

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Renalase Overexpression-Mediated Excessive Metabolism of Peripheral Dopamine, DOPAL Accumulation, and α-Synuclein Aggregation in Baroreflex Afferents Contribute to Neuronal Degeneration and Autonomic Dysfunction.

Xiong X, Xu YZ, Zhang Y, Zhang HF, Dou TM, Li XY, Xu ZY, Cui CP, Li XL, Li BY.

Biomedicines · 2025-05-20

DOI: 10.3390/biomedicines13051243PMID: 40427069

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Source record

Microbiome signature of Parkinson disease in healthy and genetically at-risk individuals

Menozzi E, Meslier V, Ren Y, Geiger M, Macnaughtan J, Avenali M, Gilles M, Galandra C, Mitrotti P, Gallo L, Famechon A, Lucas Del Pozo S, Mezabrovschi R, Koletsi S, Loefflad N, Yalkic S, Limbachiya N, Blottière H, Morabito C, David A, Quinquis B, Pons N, Valzania F, Cavallieri F, Fioravanti V, Toschi G, Blandini F, Ehrlich SD, Almeida M, Schapira AH.

· 2025-05-19

DOI: 10.1101/2025.05.19.25327907

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

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