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“Parkinson LRRK2” Clear search

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The p.Gly2019Ser is a common LRRK2 pathogenic variant among Egyptians with familial and sporadic Parkinson's disease.

William MB, Hamed S, Shalash A, Khedr EM, Yousef MH, El-Jaafary S, Fawi G, Helmy A, Hamid E, Essam M, Lee H, Jama A, Koraym M, Mahmoud DM, Elfarrash S, Elsaid Y, Gabr AS, Shebl N, Abdelwahhab N, Belal TM, Elsayed NAB, El-Gamal M, Elgamal S, Ragab S, Mekky J, Aly L, Nabhan S, Ragab G, Hussein MA, Hegazy MT, Houlden H, Salama M, Rizig M.

NPJ Parkinsons Dis · 2024-11-06

DOI: 10.1038/s41531-024-00826-8PMID: 39505921

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein.

Li F, Ackloo S, Arrowsmith CH, Ban F, Barden CJ, Beck H, Beránek J, Berenger F, Bolotokova A, Bret G, Breznik M, Carosati E, Chau I, Chen Y, Cherkasov A, Corte DD, Denzinger K, Dong A, Draga S, Dunn I, Edfeldt K, Edwards A, Eguida M, Eisenhuth P, Friedrich L, Fuerll A, Gardiner SS, Gentile F, Ghiabi P, Gibson E, Glavatskikh M, Gorgulla C, Guenther J, Gunnarsson A, Gusev F, Gutkin E, Halabelian L, Harding RJ, Hillisch A, Hoffer L, Hogner A, Houliston S, Irwin JJ, Isayev O, Ivanova A, Jacquemard C, Jarrett AJ, Jensen JH, Kireev D, Kleber J, Koby SB, Koes D, Kumar A, Kurnikova MG, Kutlushina A, Lessel U, Liessmann F, Liu S, Lu W, Meiler J, Mettu A, Minibaeva G, Moretti R, Morris CJ, Narangoda C, Noonan T, Obendorf L, Pach S, Pandit A, Perveen S, Poda G, Polishchuk P, Puls K, Pütter V, Rognan D, Roskams-Edris D, Schindler C, Sindt F, Spiwok V, Steinmann C, Stevens RL, Talagayev V, Tingey D, Vu O, Walters WP, Wang X, Wang Z, Wolber G, Wolf CA, Wortmann L, Zeng H, Zepeda CA, Zhang KYJ, Zhang J, Zheng S, Schapira M.

J Chem Inf Model · 2024-11-05

DOI: 10.1021/acs.jcim.4c01267PMID: 39499532

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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LRRK2 regulates production of reactive oxygen species in cell and animal models of Parkinson's disease.

Keeney MT, Rocha EM, Hoffman EK, Farmer K, Di Maio R, Weir J, Wagner WG, Hu X, Clark CL, Castro SL, Scheirer A, Fazzari M, De Miranda BR, Pintchovski SA, Shrader WD, Pagano PJ, Hastings TG, Greenamyre JT.

Sci Transl Med · 2024-10-02

DOI: 10.1126/scitranslmed.adl3438PMID: 39356746

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Levodopa-carbidopa intestinal gel for advanced Parkinson's disease: Impact of LRRK2 and GBA1 mutations.

Thaler A, Anis S, Ponger P, Fay-Karmon T, Livneh V, Faust-Socher A, Greenbaum L, Reiner J, Hilel A, Shabtai H, Alcalay RN, Djaldetti R, Hassin-Baer S, Ezra A, Mirelman A, Giladi N, Gurevich T.

Parkinsonism Relat Disord · 2024-08-28

DOI: 10.1016/j.parkreldis.2024.107115PMID: 39208588

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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