15.286 articles found

Autoantibody profiles in Alzheimer´s, Parkinson´s, and dementia with Lewy bodies: altered IgG affinity and IgG/IgM/IgA responses to alpha-synuclein, amyloid-beta, and tau in disease-specific pathological patterns.

Knecht L, Dalsbøl K, Simonsen AH, Pilchner F, Ross JA, Winge K, Salvesen L, Bech S, Hejl AM, Løkkegaard A, Hasselbalch SG, Dodel R, Aznar S, Waldemar G, Brudek T, Folke J.

J Neuroinflammation · 2024-12-03

DOI: 10.1186/s12974-024-03293-3PMID: 39627772

Epigenetic Modifiers: Exploring the Roles of Histone Methyltransferases and Demethylases in Cancer and Neurodegeneration.

Reed L, Abraham J, Patel S, Dhar SS.

Biology (Basel) · 2024-12-03

DOI: 10.3390/biology13121008PMID: 39765675

Letter to the editor: Exposure factors and clinical characteristics associated with Parkinson's disease in GBA1 variant carriers: A Chinese GBA1-PD intrafamilial survey.

Huang M.

Parkinsonism Relat Disord · 2024-12-03

DOI: 10.1016/j.parkreldis.2024.107222PMID: 39645415

LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis

Pei J, Oliveira NL, Recinto SJ, Kazanova A, Queiroz-Junior CM, Li Z, Couto K, Westfall S, King IL, Ribeiro CT, Milnerwood AJ, Desjardins M, Thanabalasuriar A, Stratton JA, Gruenheid S.

· 2024-12-02

DOI: 10.1101/2024.11.26.625468

Autonomic nervous system dysfunction in idiopathic REM sleep behavior disorder as a short-term risk for a synucleinopathy.

Navarro-Otano J, Llansó L, Alejaldre A, Diez L, Santamaría J, Iranzo A.

J Neurol · 2024-12-02

DOI: 10.1007/s00415-024-12787-2PMID: 39621109

Genetic Mutations in Cell Junction Proteins Associated with Brain Calcification.

Yang D, Jiang Z, Huang H, Wang L, Ying C, Chen Y, Lu Y, Zhang T, Zhu Y, Wang S, Wang Y, Guo Y, Wang H, Cen Z, Luo W.

Mov Disord · 2024-12-02

DOI: 10.1002/mds.30068PMID: 39620489

Liquid-liquid phase separation of Tau and α-synuclein: a new target for treating comorbidity in neurodegeneration.

Foressi NN, Rodríguez LC, Celej MS.

Biophys Rev · 2024-12-02

DOI: 10.1007/s12551-024-01259-6PMID: 40376419

RXR nuclear receptor signaling modulates lipid metabolism and triggers lysosomal clearance of alpha-synuclein in neuronal models of synucleinopathy

Tripathi A, Alnakhala H, Brontesi L, Selkoe D, Dettmer U.

Cell. Mol. Life Sci · 2024-12-01

Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson’s disease

Ding L, Lu L, Zheng S, Zhang Z, Huang X, Ma R, Zhang M, Xu Z, Chen M, Guo Z, Zhu S, Gong J, Mao H, Zhang W, Xu P.

Cell. Mol. Life Sci · 2024-12-01

Protein tyrosine phosphatase receptor type O serves as a key regulator of insulin resistance-induced α-synuclein aggregation in Parkinson’s disease

Tan S, Chi H, Wang P, Zhao R, Zhang Q, Gao Z, Xue H, Tang Q, Li G.

Cell. Mol. Life Sci · 2024-12-01

α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway

Jia C, Tian L, Cheng C, Zhang J, Al-Nusaif M, Li T, Yang H, Lin Y, Li S, Le W.

Cell. Mol. Life Sci · 2024-12-01

LRP10 and α-synuclein transmission in Lewy body diseases

Carreras Mascaro A, Grochowska MM, Boumeester V, Dits NFJ, Bilgiҫ EN, Breedveld GJ, Vergouw L, de Jong FJ, van Royen ME, Bonifati V, Mandemakers W.

Cell. Mol. Life Sci · 2024-12-01