15.286 articles found

Lysosomal dysfunction in α-synuclein pathology: molecular mechanisms and therapeutic strategies

Dai L, Liu M, Ke W, Chen L, Fang X, Zhang Z.

Cell. Mol. Life Sci · 2024-12-01

GENETIC AND SEROLOGICAL BIOMARKERS AS PREDICTORS OF PARKINSON’S DISEASE COGNITIVE IMPAIRMENT: A SYSTEMATIC REVIEW

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Innovation in aging · 2024-12-01

Large‐scale discovery of novel shared genetic etiology between stroke and neurodegenerative diseases like Dementia, Multiple sclerosis, Parkinson’s Disease, Amyotrophic Lateral Sclerosis

Khamkar A, Chauhan G.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024-12-01

Autophagy Deficits Underly Selective Neuronal Vulnerability to Alpha Synuclein Fibrils in Alzheimer’s and Parkinson’s iPSC Derived Neurons

Abey A, Ng B, Heon‐Roberts R, Carlyle B, Bengoa‐Vergniory N, Wade‐Martins R.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024-12-01

Characterization and Evaluation of Alpha‐Synuclein Aggregates: Unveiling Their Potential as a Biomarker for Parkinson's Disease (PD)

Debarnot C, Challagundla M, Kleinert C, Schulz M, Henn C, Boehm N, Richter M.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024-12-01

Associations between basal forebrain volume and cognitive decline in GBA and LRRK2 mutation carriers from asymptomatic stages to Parkinson’s disease

Schumacher J, Teipel S, Storch A.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024-12-01

Serum Alpha‐Synuclein and Inflammatory Markers profile in an Egyptian Alzheimer’s and Parkinson’s Diseases patients: A Pilot Study

Heikal S.

Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024-12-01

Electroencephalogram rhythmic and arrhythmic spectral components and functional connectivity at resting state may predict the development of synucleinopathies in idiopathic rapid eye movement sleep behavior disorder.

Hernandez J, Lina JM, Dubé J, Lafrenière A, Gagnon JF, Montplaisir JY, Postuma RB, Carrier J.

Sleep · 2024-12-01

DOI: 10.1093/sleep/zsae074PMID: 38497896

Gba1 E326K renders motor and non-motor symptoms with pathological α-synuclein, tau and glial activation.

Kweon SH, Ryu HG, Kwon SH, Park H, Lee S, Kim NS, Ma SX, Jee HJ, Kim S, Ko HS.

Brain · 2024-12-01

DOI: 10.1093/brain/awae222PMID: 38976650

eQTL mapping in transgenic alpha-synuclein carrying Caenorhabditis elegans recombinant inbred lines.

Huang Y, Wang YA, van Sluijs L, Vogels DHJ, Chen Y, Tegelbeckers VIP, Schoonderwoerd S, Riksen JAG, Kammenga JE, Harvey SC, Sterken MG.

Hum Mol Genet · 2024-12-01

DOI: 10.1093/hmg/ddae148PMID: 39439404

Transcranial optogenetic brain modulator for precise bimodal neuromodulation in multiple brain regions.

Shin H, Nam MH, Lee SE, Yang SH, Yang E, Jung JT, Kim H, Woo J, Cho Y, Yoon Y, Cho IJ.

Nat Commun · 2024-11-30

DOI: 10.1038/s41467-024-54759-0PMID: 39613730

Editorial: Intersection of neural activity, synuclein and Parkinson's disease.

Nakamura K.

Exp Neurol · 2024-11-30

DOI: 10.1016/j.expneurol.2024.115091PMID: 39645521