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Manganese Exposure Enhances the Release of Misfolded α-Synuclein via Exosomes by Impairing Endosomal Trafficking and Protein Degradation Mechanisms.

Rokad D, Harischandra DS, Samidurai M, Chang YT, Luo J, Lawana V, Sarkar S, Palanisamy BN, Manne S, Kim D, Zenitsky G, Jin H, Anantharam V, Willette A, Kanthasamy A, Kanthasamy AG.

Int J Mol Sci · 2024-11-14

DOI: 10.3390/ijms252212207PMID: 39596274

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The Effect of the Optogenetic Stimulation of Astrocytes on Neural Network Activity in an In Vitro Model of Alzheimer's Disease.

Mitroshina EV, Kalinina EP, Kalyakulina AI, Teplyakova AV, Vedunova MV.

Int J Mol Sci · 2024-11-14

DOI: 10.3390/ijms252212237PMID: 39596305

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Correction: Nanorod-associated plasmonic circular dichroism monitors the handedness and composition of α-synuclein fibrils from Parkinson's disease models and post-mortem brain.

Longhena F, Boujelbene R, Brembati V, Sandre M, Bubacco L, Abbate S, Longhi G, Bellucci A.

Nanoscale · 2024-11-13

DOI: 10.1039/d4nr90202ePMID: 39494611

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STAT3 Inhibitor Increases α-Synuclein in PFF-Treated Astroglia Cells by Dysregulating Autophagy and Potentially Affects Exosome Biogenesis.

Luo Y, Zang N, Tang Y, Chen H, Liu H, Wang L, Xu P.

Neuromolecular Med · 2024-11-13

DOI: 10.1007/s12017-024-08812-2PMID: 39537842

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α-Synuclein Oligomers in Skin Biopsies Predict the Worsening of Cognitive Functions in Parkinson's Disease: A Single-Center Longitudinal Cohort Study.

Contaldi E, Basellini MJ, Mazzetti S, Calogero AM, Colombo A, Cereda V, Innocenti G, Ferri V, Calandrella D, Isaias IU, Pezzoli G, Cappelletti G.

Int J Mol Sci · 2024-11-13

DOI: 10.3390/ijms252212176PMID: 39596242

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Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons.

Lin YE, Jaimon E, Tonelli F, Pfeffer SR.

Life Sci Alliance · 2024-11-13

DOI: 10.26508/lsa.202402922PMID: 39537338

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GDNF alleviates depression in Parkinson's disease by inhibiting α-synuclein aggregation and facilitating DA transmission from VTA to NAc

Chen J, Ling Z, Lv M, Xu W, Chen S, Shao L, Ma Z, Wang C, Song Y, Tang C.

· 2024-11-12

DOI: 10.21203/rs.3.rs-5365953/v1

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α-Synuclein ubiquitination - functions in proteostasis and development of Lewy bodies.

Ho HH, Wing SS.

Front Mol Neurosci · 2024-11-12

DOI: 10.3389/fnmol.2024.1498459PMID: 39600913

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Neuroprotective potential of Epigenetic modulators, its regulation and therapeutic approaches for the management of Parkinson's disease.

Kumari S, Gupta S, Sukhija R, Gurjar S, Dubey SK, Taliyan R.

Eur J Pharmacol · 2024-11-12

DOI: 10.1016/j.ejphar.2024.177123PMID: 39536854

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Molecular dynamics studies reveal the structural impacts of LRRK2 R1441C and LRRK2 D1994A mutations in Parkinson's disease.

Rahman RA, Zaman B, Islam MS, Rashid MH.

Biochem Biophys Rep · 2024-11-12

DOI: 10.1016/j.bbrep.2024.101866PMID: 39610832

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New prospects for 89Zr-immuno-PET in brain applications - Alpha-synucleinopathies.

Wuensche TE, Pereira PM, Windhorst AD, Bjerregaard-Andersen K, Sotty F, Kallunki P, Jensen A, Bang-Andersen B, van Dongen GAMS, Beaino W, Vugts DJ.

Nucl Med Biol · 2024-11-12

DOI: 10.1016/j.nucmedbio.2024.108969PMID: 39591759

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Acute introduction of monomeric or multimeric α-synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant synapses.

Román-Vendrell C, Wallace JN, Watson AH, Celikag M, Bartels T, Morgan JR.

J Physiol · 2024-11-12

DOI: 10.1113/jp286281PMID: 39530449

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.286 articles found

Manganese Exposure Enhances the Release of Misfolded α-Synuclein via Exosomes by Impairing Endosomal Trafficking and Protein Degradation Mechanisms.

The Effect of the Optogenetic Stimulation of Astrocytes on Neural Network Activity in an In Vitro Model of Alzheimer's Disease.

Correction: Nanorod-associated plasmonic circular dichroism monitors the handedness and composition of α-synuclein fibrils from Parkinson's disease models and post-mortem brain.

STAT3 Inhibitor Increases α-Synuclein in PFF-Treated Astroglia Cells by Dysregulating Autophagy and Potentially Affects Exosome Biogenesis.

α-Synuclein Oligomers in Skin Biopsies Predict the Worsening of Cognitive Functions in Parkinson's Disease: A Single-Center Longitudinal Cohort Study.

Pathogenic <i>LRRK2</i> mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons.

GDNF alleviates depression in Parkinson's disease by inhibiting α-synuclein aggregation and facilitating DA transmission from VTA to NAc

<i>α</i>-Synuclein ubiquitination - functions in proteostasis and development of Lewy bodies.

Neuroprotective potential of Epigenetic modulators, its regulation and therapeutic approaches for the management of Parkinson's disease.

Molecular dynamics studies reveal the structural impacts of LRRK2 R1441C and LRRK2 D1994A mutations in Parkinson's disease.

New prospects for <sup>89</sup>Zr-immuno-PET in brain applications - Alpha-synucleinopathies.

Acute introduction of monomeric or multimeric α-synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant synapses.

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