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Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial.

Eijsvogel P, Misra P, Concha-Marambio L, Boyd JD, Ding S, Fedor L, Hsieh YT, Sun YS, Vroom MM, Farris CM, Ma Y, de Kam ML, Radanovic I, Vissers MFJM, Mirski D, Shareghi G, Shahnawaz M, Singer W, Kremer P, Groeneveld GJ, Yu HJ, Dodart JC.

Nat Med · 2024-06-20

DOI: 10.1038/s41591-024-03101-8PMID: 38902546

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Clinical characteristics and pathophysiological properties of newly discovered LRRK2 variants associated with Parkinson's disease.

Tezuka T, Ishiguro M, Taniguchi D, Osogaguchi E, Shiba-Fukushima K, Ogata J, Ishii R, Ikeda A, Li Y, Yoshino H, Matsui T, Kaida K, Funayama M, Nishioka K, Kumazawa F, Matsubara T, Tsuda H, Saito Y, Murayama S, Imai Y, Hattori N.

Neurobiol Dis · 2024-06-18

DOI: 10.1016/j.nbd.2024.106571PMID: 38901781

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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The Role of Alpha-Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria–ER Membranes

Barbuti PA, Guardia-Laguarta C, Yun T, Chatila ZK, Flowers X, Santos BF, Larsen SB, Hattori N, Bradshaw E, Dettmer U, Fanning S, Vilas M, Reddy H, Teich AF, Krüger R, Area-Gomez E, Przedborski S.

· 2024-06-17

DOI: 10.1101/2024.06.17.599406

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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