NeuralCipher Source record
LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
DOI: 10.1101/2024.06.06.597594
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15.468 articles found
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Parkinson’s LRRK2-G2019S risk gene mutation drives sex-specific behavioral and cellular adaptations to chronic variable stress
DOI: 10.1101/2024.06.05.597647
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Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2 <sup>G2019S</sup> model of Parkinson’s disease
DOI: 10.1101/2024.06.06.597807
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Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17β-estradiol afforded protection against this manganese toxicity.
DOI: 10.1016/j.neuro.2024.05.007PMID: 38857675
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Biphenotypic Cells and α-Synuclein Accumulation in Enteric Neurons of Leucine-Rich Repeat Kinase 2 Knockout Mice.
DOI: 10.1007/s10620-024-08494-7PMID: 38849592
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5-Phenyl valeric acid attenuates α-synuclein aggregation and endoplasmic reticulum stress in rotenone-induced Parkinson's disease rats: A molecular mechanistic study.
DOI: 10.1016/j.bcp.2024.116343PMID: 38852645
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Computer-Based Evaluation of α-Synuclein Pathology in Multiple System Atrophy as a Novel Tool to Recognize Disease Subtypes.
DOI: 10.1016/j.modpat.2024.100533PMID: 38852813
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Open access
LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress.
DOI: 10.1007/s11064-024-04141-9PMID: 38847910
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Study on the mechanism of gut microbiota in the pathogenetic interaction between depression and Parkinson 's disease.
DOI: 10.1016/j.brainresbull.2024.111001PMID: 38852651
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Open access
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region.
DOI: 10.1021/acs.jmedchem.3c02408PMID: 38842931
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Development of an <sup>18</sup>F-labeled azobenzothiazole tracer for α-synuclein aggregates in the brain.
DOI: 10.1039/d4ob00492bPMID: 38768281
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Alpha-Synuclein Gene Alterations Modulate Tyrosine Hydroxylase in Human iPSC-Derived Neurons in a Parkinson's Disease Animal Model.
DOI: 10.3390/life14060728PMID: 38929711
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