Scientific Literature Search

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Elevated α-synuclein levels inhibit mitophagic flux.

Kinnart I, Manders L, Heyninck T, Imberechts D, Praschberger R, Schoovaerts N, Verfaillie C, Verstreken P, Vandenberghe W.

NPJ Parkinsons Dis · 2024-04-09

DOI: 10.1038/s41531-024-00696-0PMID: 38594264

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Open access

Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders.

Flores-Fernandez JM, Pesch V, Sriraman A, Chimal-Juarez E, Amidian S, Wang X, Duckering C, Fang A, Reithofer S, Ma L, Cortez LM, Sim VL, Tamgüney G, Wille H.

Bioeng Transl Med · 2024-04-09

DOI: 10.1002/btm2.10665PMID: 39036077

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Open access

Thrombomodulin reduces α-synuclein generation and ameliorates neuropathology in a mouse model of Parkinson's disease.

Niu XY, Xie XX, Tuo HZ, Lv CP, Huang YR, Zhu J, Liang SY, Du XY, Yang CG, Hou SJ, Sun XY, Li LJ, Cui F, Huang QX, Jia YB, Wang YJ, Liu RT.

Cell Death Discov · 2024-04-08

DOI: 10.1038/s41420-024-01939-yPMID: 38589400

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Open access

Factors Influencing Patient Disclosure of Parkinson's Disease Genetic Testing Results to Relatives.

Schulze J, Dhaliwal JK, Miller M, Quinn E, Wetherill L, Cook L.

Mov Disord Clin Pract · 2024-04-08

DOI: 10.1002/mdc3.14043PMID: 38586948

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Open access

Suppression of Glioblastoma Stem Cell Potency and Tumor Growth via LRRK2 Inhibition.

Park S, Kim KH, Bae YH, Oh YT, Shin H, Kwon HJ, Kim CI, Kim SS, Choi HG, Park JB, Lee BD.

Int J Stem Cells · 2024-04-08

DOI: 10.15283/ijsc24032PMID: 38584542

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Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases.

Moors TE, Morella ML, Bertran-Cobo C, Geut H, Udayar V, Timmermans-Huisman E, Ingrassia AMT, Brevé JJP, Bol JGJM, Bonifati V, Jagasia R, van de Berg WDJ.

Acta Neuropathol · 2024-04-06

DOI: 10.1007/s00401-024-02707-zPMID: 38581586

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Mitophagy Upregulation Occurs Early in the Neurodegenerative Process Mediated by α-Synuclein.

Hui S, George J, Kapadia M, Chau H, Bariring Z, Earnshaw R, Shafiq K, Kalia LV, Kalia SK.

Mol Neurobiol · 2024-04-06

DOI: 10.1007/s12035-024-04131-6PMID: 38581539

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Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation.

Valderhaug VD, Ramstad OH, van de Wijdeven R, Heiney K, Nichele S, Sandvig A, Sandvig I.

Front Cell Neurosci · 2024-04-05

DOI: 10.3389/fncel.2024.1366098PMID: 38644975

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Open access

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy.

Parmasad JA, Ricke KM, Nguyen B, Stykel MG, Buchner-Duby B, Bruce A, Geertsma HM, Lian E, Lengacher NA, Callaghan SM, Joselin A, Tomlinson JJ, Schlossmacher MG, Stanford WL, Ma J, Brundin P, Ryan SD, Rousseaux MWC.

Cell Death Dis · 2024-04-04

DOI: 10.1038/s41419-024-06534-8PMID: 38575601

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Fibrillar Alpha-Synuclein Alters the Intracellular Chaperone Levels within Hours of Its Internalization.

Çamoğlu T, Yurttaş Z, Kına ÜY, Akkuş Süt P, Sahin F, Dursun E, Gezen-Ak D.

ACS Omega · 2024-04-04

DOI: 10.1021/acsomega.3c10036PMID: 38645348

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Unraveling Dysregulated Cell Signaling Pathways, Genetic and Epigenetic Mysteries of Parkinson's Disease.

Hamidpour SK, Amiri M, Ketabforoush AHME, Saeedi S, Angaji A, Tavakol S.

Mol Neurobiol · 2024-04-04

DOI: 10.1007/s12035-024-04128-1PMID: 38573414

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Combined detrimental effect of male sex and GBA1 variants on cognitive decline in Parkinson’s Disease

Caminiti SP, Avenali M, Galli A, Malito R, Cuconato G, Pilotto A, Padovani A, Blandini F, Perani D, Tassorelli C, Valente EM, Parkinson’s Progression Markers Initiative (PPMI).

· 2024-04-03

DOI: 10.1101/2024.04.02.24305191

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.469 articles found

Elevated α-synuclein levels inhibit mitophagic flux.

Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders.

Thrombomodulin reduces α-synuclein generation and ameliorates neuropathology in a mouse model of Parkinson's disease.

Factors Influencing Patient Disclosure of Parkinson's Disease Genetic Testing Results to Relatives.

Suppression of Glioblastoma Stem Cell Potency and Tumor Growth via LRRK2 Inhibition.

Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases.

Mitophagy Upregulation Occurs Early in the Neurodegenerative Process Mediated by α-Synuclein.

Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation.

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy.

Fibrillar Alpha-Synuclein Alters the Intracellular Chaperone Levels within Hours of Its Internalization.

Unraveling Dysregulated Cell Signaling Pathways, Genetic and Epigenetic Mysteries of Parkinson's Disease.

Combined detrimental effect of male sex and GBA1 variants on cognitive decline in Parkinson’s Disease

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