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Epigenetics and the neurodegenerative process.

Słowikowski B, Owecki W, Jeske J, Jezierski M, Draguła M, Goutor U, Jagodziński PP, Kozubski W, Dorszewska J.

Epigenomics · 2024-03-21

DOI: 10.2217/epi-2023-0416PMID: 38511224

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Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.

Fujita M, Gao Z, Zeng L, McCabe C, White CC, Ng B, Green GS, Rozenblatt-Rosen O, Phillips D, Amir-Zilberstein L, Lee H, Pearse RV, Khan A, Vardarajan BN, Kiryluk K, Ye CJ, Klein HU, Wang G, Regev A, Habib N, Schneider JA, Wang Y, Young-Pearse T, Mostafavi S, Bennett DA, Menon V, De Jager PL.

Nat Genet · 2024-03-21

DOI: 10.1038/s41588-024-01685-yPMID: 38514782

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Open access

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors.

Dou D, Aiken J, Holzbaur ELF.

J Cell Biol · 2024-03-21

DOI: 10.1083/jcb.202307092PMID: 38512027

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Open access

CASM mediates LRRK2 recruitment and activation under lysosomal stress.

Kuwahara T, Iwatsubo T.

Autophagy · 2024-03-21

DOI: 10.1080/15548627.2024.2330032PMID: 38497477

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Expert Commentary: A new genetic variant, presenting as young onset rapidly progressive dementia and parkinsonism.

Uribe Roca MC.

Parkinsonism Relat Disord · 2024-03-21

DOI: 10.1016/j.parkreldis.2024.106946PMID: 38555267

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Rapid FRET Assay for the Early Detection of Alpha-Synuclein Aggregation in Parkinson's Disease.

Yu H, Feng R, Chen F, Wu Z, Li D, Qiu X.

ACS Chem Neurosci · 2024-03-20

DOI: 10.1021/acschemneuro.3c00617PMID: 38506367

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The role of genetics in the treatment of dystonia with deep brain stimulation: Systematic review and Meta-analysis.

Sarva H, Rodriguez-Porcel F, Rivera F, Gonzalez CD, Barkan S, Tripathi S, Gatto E, Ruiz PG, Rare Movement Disorders Study Group of the International Parkinsons and Movement Disorders Society.

J Neurol Sci · 2024-03-20

DOI: 10.1016/j.jns.2024.122970PMID: 38520940

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Artificial intelligence-driven drug repositioning uncovers efavirenz as a modulator of α-synuclein propagation: Implications in Parkinson's disease.

Kim JB, Kim SJ, So M, Kim DK, Noh HR, Kim BJ, Choi YR, Kim D, Koo H, Kim T, Woo HG, Park SM.

Biomed Pharmacother · 2024-03-20

DOI: 10.1016/j.biopha.2024.116442PMID: 38513596

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The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons

Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, Pellitero Ed, Chen CX, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Waters C, Monchi O, Dauvilliers Y, Dupre N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, HassinBaer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z, Fon EA.

· 2024-03-19

DOI: 10.21203/rs.3.rs-3979098/v1

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A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs.

Geertsma HM, Fisk ZA, Sauline L, Prigent A, Kurgat K, Callaghan SM, aSCENT-PD Consortium, Henderson MX, Rousseaux MWC.

NPJ Parkinsons Dis · 2024-03-19

DOI: 10.1038/s41531-024-00672-8PMID: 38504090

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Open access

Interplay of α-synuclein with Lipid Membranes: Cooperative Adsorption, Membrane Remodeling and Coaggregation.

Makasewicz K, Linse S, Sparr E.

JACS Au · 2024-03-19

DOI: 10.1021/jacsau.3c00579PMID: 38665673

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Open access

Characterization of α-synuclein oligomers formed in the presence of lipid vesicles.

Dasari AKR, Sengupta U, Viverette E, Borgnia MJ, Kayed R, Lim KH.

Biochem Biophys Rep · 2024-03-19

DOI: 10.1016/j.bbrep.2024.101687PMID: 38545462

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.469 articles found

Epigenetics and the neurodegenerative process.

Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors.

CASM mediates LRRK2 recruitment and activation under lysosomal stress.

Expert Commentary: A new genetic variant, presenting as young onset rapidly progressive dementia and parkinsonism.

Rapid FRET Assay for the Early Detection of Alpha-Synuclein Aggregation in Parkinson's Disease.

The role of genetics in the treatment of dystonia with deep brain stimulation: Systematic review and Meta-analysis.

Artificial intelligence-driven drug repositioning uncovers efavirenz as a modulator of α-synuclein propagation: Implications in Parkinson's disease.

The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons

A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs.

Interplay of α-synuclein with Lipid Membranes: Cooperative Adsorption, Membrane Remodeling and Coaggregation.

Characterization of α-synuclein oligomers formed in the presence of lipid vesicles.

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