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Single-Molecule Imaging Reveals Differential Stability of Alpha-Synuclein Aggregates

Wang S, Zhang SJ, Gilboa T, Kang J, Kuzkina A, Kannarkat GT, Chen L, Shih WM, Chen-Plotkin AS, Khurana V, Walt DR.

· 2026-07-04

DOI: 10.64898/2026.06.30.735576

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α-Synuclein regulates monoamine transporter capacity and amphetamine-induced efflux via modulation of transporter expression.

Ludwig I, Moser S, Lukenic M, Connor M, Sofic A, Kaltenbrunner S, Pätzold C, Hausleitner A, Gilbert C, Sucic S, Roblek M, Steinkellner T.

J Pharmacol Exp Ther · 2026-07-04

DOI: 10.1016/j.jpet.2026.104981PMID: 42509123

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No genetic evidence for <i>SLC7A11</i> involvement in Parkinson’s Disease

Lee Y, Parlar SC, Somerville E, Senkevich K, Teferra M, Gan-Or Z.

· 2026-07-02

DOI: 10.64898/2026.07.01.26357025

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The Genetic Landscape of Parkinson’s Disease in V4 countries of Central Europe - the CEGEMOD study

Ostrozovicova M, Lackova A, Grofik M, Holly P, Klivenyi P, Kovacs N, Necpal J, Smilowska K, Straka I, Tamas G, Atputhavadivel A, Baloghova J, Deptova J, Dusek P, Han V, Hornak M, Jech R, Kalinova K, Klimcakova L, Kulcsarova K, Kurca E, Lee H, Magocova V, Marekova M, Murphy D, Neupauerova J, Orkuty S, Papikova J, Pinter D, Rabajdova M, Ruzicka E, Serranova T, Soos K, Svorenova T, Valkovic P, Zarubova K, Gdovinova Z, Rizig M, Houlden H, Skorvanek M.

· 2026-07-02

DOI: 10.64898/2026.06.30.26356950

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In Vitro-Prepared A30P Alpha-Synuclein Fibrils Adopt the Conserved and Disease-Relevant Greek Key Fold.

Milchberg MH, Warmuth OA, Borcik CG, Han R, Harding BD, DeZonia B, Dhavale DD, Pierson JA, Kotzbauer PT, Wright ER, Schwieters CD, Rienstra CM.

J Phys Chem B · 2026-07-02

DOI: 10.1021/acs.jpcb.6c02786PMID: 42389901

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Characterizing Cutaneous α-Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes.

Jin Y, Yang T, Liu M, Luo H, Yuan J, Zhang K, Han X, Yang J, Xu Y.

Ann Clin Transl Neurol · 2026-07-02

DOI: 10.1002/acn3.70465PMID: 42394373

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Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Vidailhet M.

Curr Opin Neurol · 2026-07-02

DOI: 10.1097/wco.0000000000001507PMID: 42388031

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Lipid droplets promote aberrant liquid-liquid phase separation of alpha-synuclein impairing energy homeostasis.

Cevallos J, Eubanks E, Jung S, Huang Y, Guadagno E, Jaber N, Xia Y, Wang J, Wang H, Suvvari NR, Doshi A, Ravinutala N, Mosera A, Hsu T, Mody J, Sacks B, Narayan A, Smith B, Wang M, Gottapu M, Alnakhala H, Ramalingam N, Tripathi A, Bartels T, Dettmer U, Shi Z, Dai W, Kara E.

EMBO Rep · 2026-07-02

DOI: 10.1038/s44319-026-00856-8PMID: 42393234

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R1398 is the GTP-𝛾-phosphate sensor that drives the ROC G-domain switching mechanism unique to Parkinson's disease-associated LRRK2

Hoang Q, Park Y, Wu C, Yadav R, Tennessen K, Hoang N, Hoang C, Reed X, Huang X, Cookson M, Nichols R, Liao J.

· 2026-07-01

DOI: 10.21203/rs.3.rs-10121216/v1

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VPS35 mutation inhibits PINK1/parkin-mediated mitophagy via increased LRRK2 kinase activity.

Manders L, Heyninck T, Imberechts D, Holst B, Krüger R, Vandenberghe W.

Brain · 2026-07-01

DOI: 10.1093/brain/awaf414PMID: 41164908

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PARP1 suppression by α7 nAChR activation attenuated α-synuclein-induced neurotoxicity in Parkinson's disease.

Ren X, Guan D, Xue F, Zhang F, Sun J, Zheng Y, Huang H, Xu ZD, Zhang J, Wang W, Zhang C.

Protein Cell · 2026-07-01

DOI: 10.1093/procel/pwag004PMID: 41581218

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Correction: Neuropathology in genetic Parkinson's disease: a focused review of pathological and clinical findings.

Barbosa PM, Parmera JB, Warner TT.

J Neural Transm (Vienna) · 2026-07-01

DOI: 10.1007/s00702-026-03136-wPMID: 41915166

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

14.359 articles found

Single-Molecule Imaging Reveals Differential Stability of Alpha-Synuclein Aggregates

α-Synuclein regulates monoamine transporter capacity and amphetamine-induced efflux via modulation of transporter expression.

No genetic evidence for <i>SLC7A11</i> involvement in Parkinson’s Disease

The Genetic Landscape of Parkinson’s Disease in V4 countries of Central Europe - the CEGEMOD study

In Vitro-Prepared A30P Alpha-Synuclein Fibrils Adopt the Conserved and Disease-Relevant Greek Key Fold.

Characterizing Cutaneous α-Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes.

Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Lipid droplets promote aberrant liquid-liquid phase separation of alpha-synuclein impairing energy homeostasis.

R1398 is the GTP-𝛾-phosphate sensor that drives the ROC G-domain switching mechanism unique to Parkinson's disease-associated LRRK2

VPS35 mutation inhibits PINK1/parkin-mediated mitophagy via increased LRRK2 kinase activity.

PARP1 suppression by α7 nAChR activation attenuated α-synuclein-induced neurotoxicity in Parkinson's disease.

Correction: Neuropathology in genetic Parkinson's disease: a focused review of pathological and clinical findings.

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