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The effect of levodopa on the blood antioxidant system and metabolome in patients with Parkinson's disease.

Abaimov DA, Fedorova TN, Shabalina AA, Silantyev AS, Konanov DN, Fedotova EY, Poleshchuk VV, Andreev MN, Trifonova OV, Maslov DL, Balashova EE, Sychev DA, Illarioshkin SN, Lokhov PG.

Biomed Khim · 2026-05-01

DOI: 10.18097/pbmcr1642PMID: 42183764

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

mTOR Inhibition Drives Mutation-Specific Remodeling of Lysosomal and Autophagic Pathways and GCase Activity in PBMC-Derived Macrophages from Patients with GBA1-Associated Parkinson's Disease.

Bezrukova A, Basharova K, Emelyanov A, Lavrinova A, Krapova A, Galkina E, Skudarnova E, Baydakova G, Miliukhina I, Zakharova E, Pchelina S, Usenko T.

Curr Issues Mol Biol · 2026-05-01

DOI: 10.3390/cimb48050473PMID: 42193078

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Efficacy and safety of intravenous prasinezumab in individuals with early-stage Parkinson's disease on stable symptomatic monotherapy (PADOVA): a phase 2b, multicentre, randomised, double-blind, placebo-controlled study.

Nikolcheva T, Pagano G, Anzures-Cabrera J, Trundell D, Kustermann T, Simuni T, Marek K, Pavese N, Seppi K, Stocchi F, Postuma RB, Pross N, Monnet A, Respondek G, Schlegel V, Boak L, Rutten-Jacobs L, Kerchner GA, Brundin P, Svoboda H, Bonni A, PADOVA Investigators, Prasinezumab Study Group.

Lancet · 2026-05-01

DOI: 10.1016/s0140-6736(26)00865-2PMID: 42208564

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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