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Exploring the focal role of LRRK2 kinase in Parkinson's disease.

Kumar S, Behl T, Sehgal A, Chigurupati S, Singh S, Mani V, Aldubayan M, Alhowail A, Kaur S, Bhatia S, Al-Harrasi A, Subramaniyan V, Fuloria S, Fuloria NK, Sekar M, Abdel Daim MM.

Environ Sci Pollut Res Int · 2022-02-11

DOI: 10.1007/s11356-022-19082-5PMID: 35147886

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Plasma Metabolite Signature Classifies Male LRRK2 Parkinson's Disease Patients.

Dong C, Honrao C, Rodrigues LO, Wolf J, Sheehan KB, Surface M, Alcalay RN, O'Day EM.

Metabolites · 2022-02-05

DOI: 10.3390/metabo12020149PMID: 35208223

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Modeling Parkinson's disease in LRRK2 mice: focus on synaptic dysfunction and the autophagy-lysosomal pathway.

Albanese F, Domenicale C, Volta M, Morari M.

Biochem Soc Trans · 2022-02-01

DOI: 10.1042/bst20211288PMID: 35225340

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LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease.

Pang SY, Lo RCN, Ho PW, Liu HF, Chang EES, Leung CT, Malki Y, Choi ZY, Wong WY, Kung MH, Ramsden DB, Ho SL.

Transl Neurodegener · 2022-01-31

DOI: 10.1186/s40035-022-00281-6PMID: 35101134

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Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice through Activating TNF-α Pathway.

Derkinderen P, de Guilhem de Lataillade A, Neunlist M, Rolli-Derkinderen M.

Mov Disord · 2022-01-31

DOI: 10.1002/mds.28948PMID: 35100471

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Reply to: Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice through Activating TNF-α Pathway.

Lin CH, Lin HY, Ho EP, Ke YC, Cheng MF, Shiue CY, Wu CH, Liao PH, Hsu AY, Chu LA, Liu YD, Lin YH, Tai YC, Shun CT, Chiu HM, Wu MS.

Mov Disord · 2022-01-29

DOI: 10.1002/mds.28947PMID: 35092086

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Differential Phospho-Signatures in Blood Cells Identify LRRK2 G2019S Carriers in Parkinson's Disease.

Garrido A, Santamaría E, Fernández-Irigoyen J, Soto M, Simonet C, Fernández M, Obiang D, Tolosa E, Martí MJ, Padmanabhan S, Malagelada C, Ezquerra M, Fernández-Santiago R.

Mov Disord · 2022-01-20

DOI: 10.1002/mds.28927PMID: 35049090

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LRRK2 R1441C mutation causing Parkinson's Disease in an Egyptian family.

Ali S, Wszolek ZK.

Neurol Neurochir Pol · 2022-01-14

DOI: 10.5603/pjnns.a2022.0008PMID: 35029295

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High-Throughput Sequencing Haplotype Analysis Indicates in <i>LRRK2</i> Gene a Potential Risk Factor for Endemic Parkinsonism in Southeastern Moravia, Czech Republic.

Kolarikova K, Vodicka R, Vrtel R, Stellmachova J, Prochazka M, Mensikova K, Bartonikova T, Furst T, Kanovsky P, Geryk J.

Life (Basel) · 2022-01-14

DOI: 10.3390/life12010121PMID: 35054514

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LRRK2 and idiopathic Parkinson's disease.

Rocha EM, Keeney MT, Di Maio R, De Miranda BR, Greenamyre JT.

Trends Neurosci · 2022-01-04

DOI: 10.1016/j.tins.2021.12.002PMID: 34991886

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Novel Macrocyclic LRRK2 Inhibitors for Treating Parkinson's Disease.

Sabnis RW.

ACS Med Chem Lett · 2022-01-03

DOI: 10.1021/acsmedchemlett.1c00687PMID: 35059119

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Recent Update on the Development of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors: A Promising Target for the Treatment of Parkinson's Disease.

Patel A, Patel S, Mehta M, Patel Y, Langaliya D, Bhalodiya S, Bambharoliya T.

Med Chem · 2022-01-01

DOI: 10.2174/1573406418666220215122136PMID: 35168510

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

1.257 articles found

Exploring the focal role of LRRK2 kinase in Parkinson's disease.

Plasma Metabolite Signature Classifies Male LRRK2 Parkinson's Disease Patients.

Modeling Parkinson's disease in LRRK2 mice: focus on synaptic dysfunction and the autophagy-lysosomal pathway.

LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease.

Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice through Activating TNF-α Pathway.

Reply to: Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice through Activating TNF-α Pathway.

Differential Phospho-Signatures in Blood Cells Identify LRRK2 G2019S Carriers in Parkinson's Disease.

LRRK2 R1441C mutation causing Parkinson's Disease in an Egyptian family.

High-Throughput Sequencing Haplotype Analysis Indicates in <i>LRRK2</i> Gene a Potential Risk Factor for Endemic Parkinsonism in Southeastern Moravia, Czech Republic.

LRRK2 and idiopathic Parkinson's disease.

Novel Macrocyclic LRRK2 Inhibitors for Treating Parkinson's Disease.

Recent Update on the Development of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors: A Promising Target for the Treatment of Parkinson's Disease.

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