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Recent updates in autonomic research: orthostatic hypotension and cognitive function in Parkinson disease and multiple system atrophy, the skin as a window into synuclein pathology, and RFC1 repeat expansions in hereditary sensory autonomic neuropathies.

Chompoopong P, Reiter-Campeau S.

Clin Auton Res · 2023-07-26

DOI: 10.1007/s10286-023-00968-4PMID: 37493897

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RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

Dou D, Aiken J, Holzbaur EL.

· 2023-07-25

DOI: 10.1101/2023.07.25.550521

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Open access

The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells.

Gorecki AM, Spencer H, Meloni BP, Anderton RS.

Biomedicines · 2023-07-25

DOI: 10.3390/biomedicines11082089PMID: 37626586

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Open access

Double Trouble: Association of Malignant Melanoma with Sporadic and Genetic Forms of Parkinson's Disease and Asymptomatic Carriers of Related Genes: A Brief Report.

Koros C, Simitsi AM, Bougea A, Papagiannakis N, Antonelou R, Pachi I, Angelopoulou E, Prentakis A, Zachou A, Chrysovitsanou C, Beratis I, Fragkiadaki S, Kontaxopoulou D, Eftymiopoulou E, Stanitsa E, Potagas C, Papageorgiou SG, Karavasilis E, Velonakis G, Prassopoulos V, Geronicola-Trapali X, Stefanis L.

Medicina (Kaunas) · 2023-07-25

DOI: 10.3390/medicina59081360PMID: 37629650

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Blood-Based α-Synuclein Seeding-A New Era for Identifying Parkinsonian Syndromes.

Borsche M, Berg D.

Mov Disord · 2023-07-25

DOI: 10.1002/mds.29555PMID: 37489601

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E46K Mutation of α-Synuclein Preorganizes the Intramolecular Interactions Crucial for Aggregation.

Huang D, Guo C.

J Chem Inf Model · 2023-07-25

DOI: 10.1021/acs.jcim.3c00694PMID: 37489886

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Pharmacological interventions targeting α-synuclein aggregation triggered REM sleep behavior disorder and early development of Parkinson's disease.

Du L, He X, Fan X, Wei X, Xu L, Liang T, Wang C, Ke Y, Yung WH.

Pharmacol Ther · 2023-07-25

DOI: 10.1016/j.pharmthera.2023.108498PMID: 37499913

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Targeting α-synuclein and c-Abl in Parkinson's disease.

Xiao B, Tan EK.

Trends Mol Med · 2023-07-25

DOI: 10.1016/j.molmed.2023.07.004PMID: 37500382

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A Parkinson’s disease genetic risk score associates with blood DNAm on chromosome 17

Casazza W, Schaffner SL, Artaud F, Domenighetti C, Baglietto L, Schulze-Hentrich JM, Lesage S, Brice A, Corvol J, Mostafavi S, Kobor MS, Elbaz A, Dennis JK, DIG-PD Study Group.

· 2023-07-24

DOI: 10.1101/2023.07.21.23293014

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Open access

LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition.

Yadavalli N, Ferguson SM.

Proc Natl Acad Sci U S A · 2023-07-24

DOI: 10.1073/pnas.2303789120PMID: 37487100

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4-Oxo-2-nonenal-Induced α-Synuclein Oligomers Interact with Membranes in the Cell, Leading to Mitochondrial Fragmentation.

Andersen CB, Lausdahl AK, Nielsen J, Clausen MP, Mulder FAA, Otzen DE, Arnspang EC.

Biochemistry · 2023-07-24

DOI: 10.1021/acs.biochem.3c00114PMID: 37487228

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Open access

Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain.

Zhang S, Dauer K, Strohäker T, Tatenhorst L, Caldi Gomes L, Mayer S, Jung BC, Kim WS, Lee SJ, Becker S, Liesche-Starnecker F, Zweckstetter M, Lingor P.

Brain Pathol · 2023-07-24

DOI: 10.1111/bpa.13196PMID: 37485772

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.814 articles found

Recent updates in autonomic research: orthostatic hypotension and cognitive function in Parkinson disease and multiple system atrophy, the skin as a window into synuclein pathology, and RFC1 repeat expansions in hereditary sensory autonomic neuropathies.

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells.

Double Trouble: Association of Malignant Melanoma with Sporadic and Genetic Forms of Parkinson's Disease and Asymptomatic Carriers of Related Genes: A Brief Report.

Blood-Based α-Synuclein Seeding-A New Era for Identifying Parkinsonian Syndromes.

E46K Mutation of α-Synuclein Preorganizes the Intramolecular Interactions Crucial for Aggregation.

Pharmacological interventions targeting α-synuclein aggregation triggered REM sleep behavior disorder and early development of Parkinson's disease.

Targeting α-synuclein and c-Abl in Parkinson's disease.

A Parkinson’s disease genetic risk score associates with blood DNAm on chromosome 17

LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition.

4-Oxo-2-nonenal-Induced α-Synuclein Oligomers Interact with Membranes in the Cell, Leading to Mitochondrial Fragmentation.

Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain.

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