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The Genetic Basis of Probable REM Sleep Behavior Disorder in Parkinson’s Disease

Pérez-Lloret S, Chevalier G, Bordet S, Barbar H, Capani F, Udovin L, Otero-Losada M.

· 2023-06-28

DOI: 10.20944/preprints202306.2047.v1

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MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

Geng L, Gao W, Hexige S, Li Y, Zeng Y, Zhang Z, Li X, Liu Z, Gao Q, Jiang N, Yu X, Chen X, Li S, Chen L, Li A, Chen G, Shen Y, Tian M, Zhang Z, Li J.

· 2023-06-28

DOI: 10.21203/rs.3.rs-2996654/v1

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Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures

Hu J, Xia W, Zeng S, Lim Y, Tao Y, Sun Y, Zhao L, Wang H, Li D, Liu C, Li Y.

· 2023-06-28

DOI: 10.1101/2023.06.27.546682

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Open access

Unraveling Molecular and Genetic Insights into Neurodegenerative Diseases: Advances in Understanding Alzheimer's, Parkinson's, and Huntington's Diseases and Amyotrophic Lateral Sclerosis.

Ciurea AV, Mohan AG, Covache-Busuioc RA, Costin HP, Glavan LA, Corlatescu AD, Saceleanu VM.

Int J Mol Sci · 2023-06-28

DOI: 10.3390/ijms241310809PMID: 37445986

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Open access

Cerebral Microvascular Injury Induced by Lag3-Dependent α-Synuclein Fibril Endocytosis Exacerbates Cognitive Impairment in a Mouse Model of α-Synucleinopathies.

Zhang Q, Duan Q, Gao Y, He P, Huang R, Huang H, Li Y, Ma G, Zhang Y, Nie K, Wang L.

Adv Sci (Weinh) · 2023-06-28

DOI: 10.1002/advs.202301903PMID: 37381656

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Open access

Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2).

Lange LM, Avenali M, Ellis M, Illarionova A, Keller Sarmiento IJ, Tan AH, Madoev H, Galandra C, Junker J, Roopnarain K, Solle J, Wegel C, Fang ZH, Heutink P, Kumar KR, Lim SY, Valente EM, Nalls M, Blauwendraat C, Singleton A, Mencacci N, Lohmann K, Klein C, Global Parkinson’s Genetic Program (GP2).

NPJ Parkinsons Dis · 2023-06-27

DOI: 10.1038/s41531-023-00526-9PMID: 37369645

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Open access

Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays.

Anagnostou D, Sfakianaki G, Melachroinou K, Soutos M, Constantinides V, Vaikath N, Tsantzali I, Paraskevas GP, Agnaf OE, Vekrellis K, Emmanouilidou E.

Diagnostics (Basel) · 2023-06-27

DOI: 10.3390/diagnostics13132192PMID: 37443586

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Open access

Genetic Testing in Parkinson's Disease.

Pal G, Cook L, Schulze J, Verbrugge J, Alcalay RN, Merello M, Sue CM, Bardien S, Bonifati V, Chung SJ, Foroud T, Gatto E, Hall A, Hattori N, Lynch T, Marder K, Mascalzoni D, Novaković I, Thaler A, Raymond D, Salari M, Shalash A, Suchowersky O, Mencacci NE, Simuni T, Saunders-Pullman R, Klein C.

Mov Disord · 2023-06-27

DOI: 10.1002/mds.29500PMID: 37365908

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Regulation of LRRK2 mRNA stability by ATIC and its substrate AICAR through ARE-mediated mRNA decay in Parkinson's disease.

Liu Q, Zhu D, Li N, Chen S, Hu L, Yu J, Xiong Y.

EMBO J · 2023-06-27

DOI: 10.15252/embj.2022113410PMID: 37366237

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Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

Santos ABD, Thaneshwaran S, Ali LK, Leguizamón CRR, Wang Y, Kristensen MP, Langkilde AE, Kohlmeier KA.

· 2023-06-26

DOI: 10.21203/rs.3.rs-2941679/v1

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Open access

Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease.

Schonhoff AM, Figge DA, Williams GP, Jurkuvenaite A, Gallups NJ, Childers GM, Webster JM, Standaert DG, Goldman JE, Harms AS.

Nat Commun · 2023-06-26

DOI: 10.1038/s41467-023-39060-wPMID: 37365181

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Ultrastiff Amyloid-Fibril Network of α-Synuclein Formed by Surface Seeding Reaction Confirmed by Multichannel Electrodeless Quartz-Crystal-Microbalance Biosensor.

Zhou L, Hajiri T, Nakajima K, Aguirre C, Ikenaka K, Mochizuki H, Yamaguchi K, Goto Y, Ogi H.

ACS Sens · 2023-06-26

DOI: 10.1021/acssensors.3c00331PMID: 37357775

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.814 articles found

The Genetic Basis of Probable REM Sleep Behavior Disorder in Parkinson’s Disease

MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures

Unraveling Molecular and Genetic Insights into Neurodegenerative Diseases: Advances in Understanding Alzheimer's, Parkinson's, and Huntington's Diseases and Amyotrophic Lateral Sclerosis.

Cerebral Microvascular Injury Induced by Lag3-Dependent α-Synuclein Fibril Endocytosis Exacerbates Cognitive Impairment in a Mouse Model of α-Synucleinopathies.

Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2).

Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays.

Genetic Testing in Parkinson's Disease.

Regulation of LRRK2 mRNA stability by ATIC and its substrate AICAR through ARE-mediated mRNA decay in Parkinson's disease.

Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease.

Ultrastiff Amyloid-Fibril Network of α-Synuclein Formed by Surface Seeding Reaction Confirmed by Multichannel Electrodeless Quartz-Crystal-Microbalance Biosensor.

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