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Proteome Wide Association Studies of LRRK2 variants identify novel causal and druggable for Parkinson’s disease

Phillips B, Western D, Wang L, Timsina J, Sun Y, Gorijala P, Yang C, Do A, Nykänen N, Alvarez I, Aguilar M, Pastor P, Morris JC, Schindler SE, Fagan AM, Puerta R, García-González P, de Rojas I, Marquié M, Boada M, Ruiz A, Perlmutter JS, Dominantly Inherited Alzheimer Network (DIAN) Consortia, Ibanez L, Perrin RJ, Sung YJ, Cruchaga C.

· 2023-01-07

DOI: 10.1101/2023.01.05.23284241

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Diverging Parkinson’s Disease Pathology between patient-derived <i> GBA <sup>N370S</sup> , LRRK2 <sup>G2019S</sup> </i> and engineered <i> SNCA <sup>A53T</sup> </i> iPSC-derived Dopaminergic Neurons

Fathi A, Bakshy K, Zieghami L, Fiene R, Bradley R, Dickerson S, Carlson C, Schachtele S, Liu J.

· 2023-01-07

DOI: 10.1101/2023.01.06.521264

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Ubiquilin-2 regulates pathological alpha-synuclein.

Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL.

Sci Rep · 2023-01-06

DOI: 10.1038/s41598-022-26899-0PMID: 36609661

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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