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Early α-synuclein-mediated mitochondrial dysfunction in a human cell model of Parkinson's disease dementia.

Alfaidi MS, Wenger LMD, Szebényi K, Stoker TB, He X, Fazal SV, Sebestikova J, Jassim A, Gilbertson RJ, Garza R, Jakobsson J, Spillantini MG, Barker RA, Kuan WL.

Commun Biol · 2026-05-12

DOI: 10.1038/s42003-026-10134-xPMID: 42120738

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies.

Carceles-Cordon M, Brody EM, Boucher ML, Gallagher MD, Skrinak RT, Unger TL, Penner CK, Berndt AJ, Das S, Lam K, Jaenisch R, Van Deerlin V, Lee EB, Brunden K, Luk KC, Chen-Plotkin AS.

Neuron · 2026-05-12

DOI: 10.1016/j.neuron.2026.04.033PMID: 42127911

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Recruitment Strategies across the Spectrum of Neuronal Synuclein Disease.

Siderowf A, Heathers LEA, Fabrizio K, Kuhl MM, Kopil CM, Flagg E, McMahon BA, Coffey CS, Bright A, Totten M, Lemon LP, Bryan E, Prakash N, Pavese N, Bloem BR, Alcalay RN, Mirelman A, Stefanis L, Okubadejo N, Tolosa E, Tanner CM, Simuni T, Chowdhury S, Tropea TF, Marek K, Foroud T, Parkinson's Progression Markers Initiative.

Ann Neurol · 2026-05-10

DOI: 10.1002/ana.78239PMID: 42108682

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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