Scientific Literature Search

Open access

Small heterodimer partner (SHP) aggravates ER stress in Parkinson's disease-linked LRRK2 mutant astrocyte by regulating XBP1 SUMOylation.

Lee JH, Han JH, Joe EH, Jou I.

J Biomed Sci · 2021-07-07

DOI: 10.1186/s12929-021-00747-1PMID: 34229656

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Open access

Macromolecular crowding modulates α-synuclein amyloid fiber growth.

Horvath I, Kumar R, Wittung-Stafshede P.

Biophys J · 2021-07-07

DOI: 10.1016/j.bpj.2021.06.032PMID: 34242594

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Open access

PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson's Disease.

Li W, Fu Y, Halliday GM, Sue CM.

Front Cell Dev Biol · 2021-07-06

DOI: 10.3389/fcell.2021.612476PMID: 34295884

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Open access

Untangling the genetic link between type 1 and type 2 diabetes using functional genomics.

Nyaga DM, Vickers MH, Jefferies C, Fadason T, O'Sullivan JM.

Sci Rep · 2021-07-06

DOI: 10.1038/s41598-021-93346-xPMID: 34230558

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Genome-wide contribution of common Short-Tandem Repeats to Parkinson’s Disease genetic risk

Bustos BI, Billingsley K, Blauwendraat C, Gibbs JR, Gan-Or Z, Krainc D, Singleton AB, Lubbe SJ, For the International Parkinson’s Disease Genomics Consortium (IPDGC).

· 2021-07-05

DOI: 10.1101/2021.07.01.21259645

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Open access

Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson's Disease Models.

Verma DK, Seo BA, Ghosh A, Ma SX, Hernandez-Quijada K, Andersen JK, Ko HS, Kim YH.

Cells · 2021-07-05

DOI: 10.3390/cells10071694PMID: 34359864

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Machine learning identifies six genetic variants and alterations in the Heart Atrial Appendage as key contributors to PD risk predictivity

Ho D, Schierding W, Farrow S, Cooper AA, Kempa-Liehr AW, O’Sullivan JM.

· 2021-07-03

DOI: 10.1101/2021.06.29.21259734

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Open access

α-Synuclein E46K Mutation and Involvement of Oxidative Stress in a Drosophila Model of Parkinson's Disease.

Reiszadeh Jahromi S, Ramesh SR, Finkelstein DI, Haddadi M.

Parkinsons Dis · 2021-07-03

DOI: 10.1155/2021/6621507PMID: 34285796

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Intracranial administration of alpha-synuclein fibrils in A30P-synuclein transgenic mice causes robust synucleinopathy and microglial induction.

Gentzel RC, Toolan D, Jinn S, Schachter JB, Ma L, Kahle PJ, Smith SM, Marcus JN.

Neurobiol Aging · 2021-07-03

DOI: 10.1016/j.neurobiolaging.2021.05.012PMID: 34225000

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Open access

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway.

Samidurai M, Palanisamy BN, Bargues-Carot A, Hepker M, Kondru N, Manne S, Zenitsky G, Jin H, Anantharam V, Kanthasamy AG, Kanthasamy A.

Front Aging Neurosci · 2021-07-02

DOI: 10.3389/fnagi.2021.661505PMID: 34276337

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Open access

Glucosylceramide Associated with Gaucher Disease Forms Amyloid-like Twisted Ribbon Fibrils That Induce α-Synuclein Aggregation.

Paul A, Jacoby G, Laor Bar-Yosef D, Beck R, Gazit E, Segal D.

ACS Nano · 2021-07-02

DOI: 10.1021/acsnano.1c02957PMID: 34213307

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Open access

Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration.

Carola G, Malagarriga D, Calatayud C, Pons-Espinal M, Blasco-Agell L, Richaud-Patin Y, Fernandez-Carasa I, Baruffi V, Beltramone S, Molina E, Dell'Era P, Toledo-Aral JJ, Tolosa E, Muotri AR, Garcia Ojalvo J, Soriano J, Raya A, Consiglio A.

NPJ Parkinsons Dis · 2021-07-02

DOI: 10.1038/s41531-021-00198-3PMID: 34215735

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.468 articles found

Small heterodimer partner (SHP) aggravates ER stress in Parkinson's disease-linked LRRK2 mutant astrocyte by regulating XBP1 SUMOylation.

Macromolecular crowding modulates α-synuclein amyloid fiber growth.

<i>PARK</i> Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson's Disease.

Untangling the genetic link between type 1 and type 2 diabetes using functional genomics.

Genome-wide contribution of common Short-Tandem Repeats to Parkinson’s Disease genetic risk

Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson's Disease Models.

Machine learning identifies six genetic variants and alterations in the Heart Atrial Appendage as key contributors to PD risk predictivity

<i>α</i>-Synuclein E46K Mutation and Involvement of Oxidative Stress in a <i>Drosophila</i> Model of Parkinson's Disease.

Intracranial administration of alpha-synuclein fibrils in A30P-synuclein transgenic mice causes robust synucleinopathy and microglial induction.

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway.

Glucosylceramide Associated with Gaucher Disease Forms Amyloid-like Twisted Ribbon Fibrils That Induce α-Synuclein Aggregation.

Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration.

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