Scientific Literature Search

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Biomarkers and the Role of α-Synuclein in Parkinson's Disease.

Du T, Wang L, Liu W, Zhu G, Chen Y, Zhang J.

Front Aging Neurosci · 2021-03-23

DOI: 10.3389/fnagi.2021.645996PMID: 33833675

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Development of a Sensitive Diagnostic Assay for Parkinson Disease Quantifying α-Synuclein-Containing Extracellular Vesicles.

Hong Z, Tian C, Stewart T, Aro P, Soltys D, Bercow M, Sheng L, Borden K, Khrisat T, Pan C, Zabetian CP, Peskind ER, Quinn JF, Montine TJ, Aasly J, Shi M, Zhang J.

Neurology · 2021-03-23

DOI: 10.1212/wnl.0000000000011853PMID: 34032594

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Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.

Perni M, van der Goot A, Limbocker R, van Ham TJ, Aprile FA, Xu CK, Flagmeier P, Thijssen K, Sormanni P, Fusco G, Chen SW, Challa PK, Kirkegaard JB, Laine RF, Ma KY, Müller MBD, Sinnige T, Kumita JR, Cohen SIA, Seinstra R, Kaminski Schierle GS, Kaminski CF, Kaminski CF, Barbut D, De Simone A, Knowles TPJ, Zasloff M, Nollen EAA, Vendruscolo M, Dobson CM.

Front Cell Dev Biol · 2021-03-22

DOI: 10.3389/fcell.2021.552549PMID: 33829010

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Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration in Drosophila.

Bridi JC, Bereczki E, Smith SK, Poças GM, Kottler B, Domingos PM, Elliott CJ, Aarsland D, Hirth F.

Brain Commun · 2021-03-22

DOI: 10.1093/braincomms/fcab049PMID: 33997781

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The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells.

Cascella R, Chen SW, Bigi A, Camino JD, Xu CK, Dobson CM, Chiti F, Cremades N, Cecchi C.

Nat Commun · 2021-03-22

DOI: 10.1038/s41467-021-21937-3PMID: 33753734

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Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease.

Kim S, Wong YC, Gao F, Krainc D.

Nat Commun · 2021-03-22

DOI: 10.1038/s41467-021-22113-3PMID: 33753743

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Hydration Thermodynamics of Familial Parkinson's Disease-Linked Mutants of α-Synuclein.

Aggarwal L, Biswas P.

J Chem Inf Model · 2021-03-22

DOI: 10.1021/acs.jcim.1c00034PMID: 33749266

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Progression of phosphorylated α-synuclein in Macaca fuscata.

Kawakami I, Motoda A, Hashimoto M, Shimozawa A, Masuda-Suzukake M, Ohtani R, Takase M, Kumashiro M, Samejima K, Hasegawa M.

Brain Pathol · 2021-03-22

DOI: 10.1111/bpa.12952PMID: 33754430

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Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease.

Reyes JF, Ekmark-Léwen S, Perdiki M, Klingstedt T, Hoffmann A, Wiechec E, Nilsson P, Nilsson KPR, Alafuzoff I, Ingelsson M, Hallbeck M.

Acta Neuropathol Commun · 2021-03-20

DOI: 10.1186/s40478-021-01136-3PMID: 33743820

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ALDH1A1 Genetic Variations May Modulate Risk of Parkinson's Disease in Han Chinese Population.

Fan HH, Guo Q, Zheng J, Lian YZ, Huang SS, Sun Y, Zou M, Zhu JH, Zhang X.

Front Neurosci · 2021-03-19

DOI: 10.3389/fnins.2021.620929PMID: 33815038

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Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo.

Kluss JH, Mazza MC, Li Y, Manzoni C, Lewis PA, Cookson MR, Mamais A.

Mol Neurodegener · 2021-03-19

DOI: 10.1186/s13024-021-00441-8PMID: 33741046

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Il-10 signaling reduces survival in mouse models of synucleinopathy.

Cockey SG, McFarland KN, Koller EJ, Brooks MMT, Gonzalez De La Cruz E, Cruz PE, Ceballos-Diaz C, Rosario AM, Levites YR, Borchelt DR, Golde TE, Giasson BI, Chakrabarty P.

NPJ Parkinsons Dis · 2021-03-19

DOI: 10.1038/s41531-021-00169-8PMID: 33741985

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

15.468 articles found

Biomarkers and the Role of α-Synuclein in Parkinson's Disease.

Development of a Sensitive Diagnostic Assay for Parkinson Disease Quantifying α-Synuclein-Containing Extracellular Vesicles.

Comparative Studies in the A30P and A53T α-Synuclein <i>C. elegans</i> Strains to Investigate the Molecular Origins of Parkinson's Disease.

Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration in <i>Drosophila</i>.

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells.

Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease.

Hydration Thermodynamics of Familial Parkinson's Disease-Linked Mutants of α-Synuclein.

Progression of phosphorylated α-synuclein in Macaca fuscata.

Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease.

<i>ALDH1A1</i> Genetic Variations May Modulate Risk of Parkinson's Disease in Han Chinese Population.

Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo.

Il-10 signaling reduces survival in mouse models of synucleinopathy.

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