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Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor.

Henderson JL, Kormos BL, Hayward MM, Coffman KJ, Jasti J, Kurumbail RG, Wager TT, Verhoest PR, Noell GS, Chen Y, Needle E, Berger Z, Steyn SJ, Houle C, Hirst WD, Galatsis P.

J Med Chem · 2014-11-17

DOI: 10.1021/jm5014055PMID: 25353650

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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TMS enhances retention of a motor skill in Parkinson's disease.

Moisello C, Blanco D, Fontanesi C, Lin J, Biagioni M, Kumar P, Brys M, Loggini A, Marinelli L, Abbruzzese G, Quartarone A, Tononi G, Di Rocco A, Ghilardi MF, Sensory Motor Integration Lab (SMILab).

Brain Stimul · 2014-11-15

DOI: 10.1016/j.brs.2014.11.005PMID: 25533243

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

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