14.936 articles found

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The LRRK2 signalling system.

Price A, Manzoni C, Cookson MR, Lewis PA.

Cell Tissue Res · 2018-01-08

DOI: 10.1007/s00441-017-2759-9PMID: 29308544

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Serum Mortalin Correlated with α-Synuclein as Serum Markers in Parkinson's Disease: A Pilot Study.

Singh AP, Bajaj T, Gupta D, Singh SB, Chakrawarty A, Goyal V, Dey AB, Dey S.

Neuromolecular Med · 2018-01-06

DOI: 10.1007/s12017-017-8475-5PMID: 29307058

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Association study of essential tremor genetic loci in Parkinson's disease.

Ross JP, Mohtashami S, Leveille E, Johnson AM, Xiong L, Dion PA, Fon E, Dauvilliers Y, Dupré N, Rouleau GA, Gan-Or Z.

Neurobiol Aging · 2018-01-06

DOI: 10.1016/j.neurobiolaging.2018.01.001PMID: 29398123

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Back to the future: new target-validated Rab antibodies for evaluating LRRK2 signalling in cell biology and Parkinson's disease.

Eyers PA.

Biochem J · 2018-01-05

DOI: 10.1042/bcj20170870PMID: 29305429

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LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT<sub>1A</sub> Receptor Upregulation in Mice.

Lim J, Bang Y, Choi JH, Han A, Kwon MS, Liu KH, Choi HJ.

J Neurosci · 2018-01-05

DOI: 10.1523/jneurosci.4051-15.2017PMID: 29305532

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Genetics and Treatment Response in Parkinson's Disease: An Update on Pharmacogenetic Studies.

Politi C, Ciccacci C, Novelli G, Borgiani P.

Neuromolecular Med · 2018-01-05

DOI: 10.1007/s12017-017-8473-7PMID: 29305687

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Levels of α- and β-synuclein regulate cellular susceptibility to toxicity from α-synuclein oligomers.

Angelova DM, Jones HBL, Brown DR.

FASEB J · 2018-01-04

DOI: 10.1096/fj.201700675rPMID: 29054856

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PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats.

Andersen MA, Wegener KM, Larsen S, Badolo L, Smith GP, Jeggo R, Jensen PH, Sotty F, Christensen KV, Thougaard A.

Toxicology · 2018-01-04

DOI: 10.1016/j.tox.2018.01.003PMID: 29307545

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Neuropathology of autonomic dysfunction in synucleinopathies.

Coon EA, Cutsforth-Gregory JK, Benarroch EE.

Mov Disord · 2018-01-03

DOI: 10.1002/mds.27186PMID: 29297596

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Pathological role of lipid interaction with α-synuclein in Parkinson's disease.

Suzuki M, Sango K, Wada K, Nagai Y.

Neurochem Int · 2018-01-03

DOI: 10.1016/j.neuint.2017.12.014PMID: 29305919

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Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.

Fan Y, Howden AJM, Sarhan AR, Lis P, Ito G, Martinez TN, Brockmann K, Gasser T, Alessi DR, Sammler EM.

Biochem J · 2018-01-02

DOI: 10.1042/bcj20170803PMID: 29127255

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Development of phospho-specific Rab protein antibodies to monitor <i>in vivo</i> activity of the LRRK2 Parkinson's disease kinase.

Lis P, Burel S, Steger M, Mann M, Brown F, Diez F, Tonelli F, Holton JL, Ho PW, Ho SL, Chou MY, Polinski NK, Martinez TN, Davies P, Alessi DR.

Biochem J · 2018-01-02

DOI: 10.1042/bcj20170802PMID: 29127256

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