14.777 articles found

Structure, Distribution, and Genetic Profile of α-Synuclein and Their Potential Clinical Application in Parkinson's Disease.

Si X, Pu J, Zhang B.

J Mov Disord · 2017-05-08

DOI: 10.14802/jmd.16061PMID: 28479587

Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss.

Grigoletto J, Pukaß K, Gamliel A, Davidi D, Katz-Brull R, Richter-Landsberg C, Sharon R.

Acta Neuropathol Commun · 2017-05-08

DOI: 10.1186/s40478-017-0439-3PMID: 28482862

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects.

Tomlinson JJ, Shutinoski B, Dong L, Meng F, Elleithy D, Lengacher NA, Nguyen AP, Cron GO, Jiang Q, Roberson ED, Nussbaum RL, Majbour NK, El-Agnaf OM, Bennett SA, Lagace DC, Woulfe JM, Sad S, Brown EG, Schlossmacher MG.

J Neural Transm (Vienna) · 2017-05-05

DOI: 10.1007/s00702-017-1726-7PMID: 28477284

Steady-State Kinetics of α-Synuclein Ferrireductase Activity Identifies the Catalytically Competent Species.

McDowall JS, Ntai I, Hake J, Whitley PR, Mason JM, Pudney CR, Brown DR.

Biochemistry · 2017-05-04

DOI: 10.1021/acs.biochem.7b00257PMID: 28452474

Enteric alpha-synuclein pathology in LRRK2-G2019S Parkinson's disease.

Rouaud T, Clairembault T, Coron E, Neunlist M, Anheim M, Derkinderen P.

Parkinsonism Relat Disord · 2017-05-03

DOI: 10.1016/j.parkreldis.2017.05.001PMID: 28483388

Novel Benzothiazole Derivatives as Fluorescent Probes for Detection of β-Amyloid and α-Synuclein Aggregates.

Watanabe H, Ono M, Ariyoshi T, Katayanagi R, Saji H.

ACS Chem Neurosci · 2017-05-03

DOI: 10.1021/acschemneuro.6b00450PMID: 28467708

Genetic Variations and mRNA Expression of NRF2 in Parkinson's Disease.

Ran C, Wirdefeldt K, Brodin L, Ramezani M, Westerlund M, Xiang F, Anvret A, Willows T, Sydow O, Johansson A, Galter D, Svenningsson P, Belin AC.

Parkinsons Dis · 2017-05-02

DOI: 10.1155/2017/4020198PMID: 28540099

The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition.

Wu KC, Liou HH, Kao YH, Lee CY, Lin CJ.

Neurobiol Dis · 2017-05-02

DOI: 10.1016/j.nbd.2017.05.001PMID: 28476637

Superoxide is the critical driver of DOPAL autoxidation, lysyl adduct formation, and crosslinking of α-synuclein

Werner-Allen JW, Levine RL, Bax A.

Biochemical and Biophysical Research Communications · 2017-05-01

Aggregation of α-Synuclein in the Gonadal Tissue of 2 Patients With Parkinson Disease.

Garrido A, Aldecoa I, Gelpi E, Tolosa E.

JAMA Neurol · 2017-05-01

DOI: 10.1001/jamaneurol.2016.6155PMID: 28288262

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.

Vicente Miranda H, Szego ÉM, Oliveira LMA, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF.

Brain · 2017-05-01

DOI: 10.1093/brain/awx056PMID: 28398476

Spine Topographical Distribution of Skin α-Synuclein Deposits in Idiopathic Parkinson Disease.

Donadio V, Incensi A, Rizzo G, Scaglione C, Capellari S, Fileccia E, Avoni P, Liguori R.

J Neuropathol Exp Neurol · 2017-05-01

DOI: 10.1093/jnen/nlx021PMID: 28402459