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Structural disorder of monomeric α-synuclein persists in mammalian cells.

Theillet FX, Binolfi A, Bekei B, Martorana A, Rose HM, Stuiver M, Verzini S, Lorenz D, van Rossum M, Goldfarb D, Selenko P.

Nature · 2016-01-25

DOI: 10.1038/nature16531PMID: 26808899

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Coupling of the non-amyloid-component (NAC) domain and the KTK(E/Q)GV repeats stabilize the α-synuclein fibrils.

Xu L, Nussinov R, Ma B.

Eur J Med Chem · 2016-01-25

DOI: 10.1016/j.ejmech.2016.01.044PMID: 26873872

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Open access

Gut Feelings About α-Synuclein in Gastrointestinal Biopsies: Biomarker in the Making?

Ruffmann C, Parkkinen L.

Mov Disord · 2016-01-22

DOI: 10.1002/mds.26480PMID: 26799450

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Stabilization of α-Synuclein Fibril Clusters Prevents Fragmentation and Reduces Seeding Activity and Toxicity.

Lam HT, Graber MC, Gentry KA, Bieschke J.

Biochemistry · 2016-01-22

DOI: 10.1021/acs.biochem.5b01168PMID: 26799377

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Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings.

Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG.

Mov Disord · 2016-01-22

DOI: 10.1002/mds.26476PMID: 26799362

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Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.

Arcuri L, Viaro R, Bido S, Longo F, Calcagno M, Fernagut PO, Zaveri NT, Calò G, Bezard E, Morari M.

Neurobiol Dis · 2016-01-22

DOI: 10.1016/j.nbd.2016.01.016PMID: 26804029

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LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity.

Karuppagounder SS, Xiong Y, Lee Y, Lawless MC, Kim D, Nordquist E, Martin I, Ge P, Brahmachari S, Jhaldiyal A, Kumar M, Andrabi SA, Dawson TM, Dawson VL.

J Chem Neuroanat · 2016-01-22

DOI: 10.1016/j.jchemneu.2016.01.007PMID: 26808467

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Synaptic failure and α-synuclein.

Calo L, Wegrzynowicz M, Santivañez-Perez J, Grazia Spillantini M.

Mov Disord · 2016-01-21

DOI: 10.1002/mds.26479PMID: 26790375

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Open access

A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo.

Delenclos M, Trendafilova T, Jones DR, Moussaud S, Baine AM, Yue M, Hirst WD, McLean PJ.

Front Neurosci · 2016-01-19

DOI: 10.3389/fnins.2015.00511PMID: 26834539

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Open access

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.

Majbour NK, Vaikath NN, van Dijk KD, Ardah MT, Ardah MT, Varghese S, Vesterager LB, Montezinho LP, Poole S, Safieh-Garabedian B, Tokuda T, Teunissen CE, Berendse HW, van de Berg WD, El-Agnaf OM.

Mol Neurodegener · 2016-01-19

DOI: 10.1186/s13024-016-0072-9PMID: 26782965

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The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

Tanji K, Miki Y, Maruyama A, Mori F, Mimura J, Itoh K, Kamitani T, Wakabayashi K.

Biochem Biophys Res Commun · 2016-01-18

DOI: 10.1016/j.bbrc.2016.01.093PMID: 26797281

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Genetic and Clinical Predictors of Deep Brain Stimulation in Young-Onset Parkinson's Disease.

Pal GD, Hall D, Ouyang B, Phelps J, Alcalay R, Pauciulo MW, Nichols WC, Clark L, Mejia-Santana H, Blasucci L, Goetz CG, Comella C, Colcher A, Gan-Or Z, Rouleau GA, Marder K, Consortium on Risk for Early Onset Parkinson's Disease (CORE-PD) Investigators.

Mov Disord Clin Pract · 2016-01-18

DOI: 10.1002/mdc3.12309PMID: 27709117

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

14.570 articles found

Structural disorder of monomeric α-synuclein persists in mammalian cells.

Coupling of the non-amyloid-component (NAC) domain and the KTK(E/Q)GV repeats stabilize the α-synuclein fibrils.

Gut Feelings About α-Synuclein in Gastrointestinal Biopsies: Biomarker in the Making?

Stabilization of α-Synuclein Fibril Clusters Prevents Fragmentation and Reduces Seeding Activity and Toxicity.

Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings.

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.

LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity.

Synaptic failure and α-synuclein.

A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo.

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.

The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

Genetic and Clinical Predictors of Deep Brain Stimulation in Young-Onset Parkinson's Disease.

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