106.818 articles found

Inhibition of de novo ceramide synthesis mitigates alpha-synuclein pathology and restores cognitive function in a Parkinson's disease mouse model

Oh C, Lee E, Park M, Park M, Kim N, Wei S, Hwang N, Ryu D, Park D, Lee G.

· 2025-08-01

DOI: 10.21203/rs.3.rs-7167930/v1

Hexosylceramides are elevated in human, mouse and cellular Parkinson's disease and cause gene upregulations in neurons mimicking responses to pathogens

Franck L, Hahnefeld L, Valek L, Klatt-Schreiner K, Wilken-Schmitz A, Alnouri M, Trautmann S, Weyer M, Thomas D, Gurke R, Offermanns S, Geisslinger G, Tegeder I.

· 2025-08-01

DOI: 10.21203/rs.3.rs-6633816/v1

Optimizing Parkinson’s Disease progression scales using computational methods

Benesh A, Alcalay RN, Mirelman A, Shamir R.

· 2025-08-01

DOI: 10.1101/2025.07.31.25332494

Sex-specific vulnerability to behavioural and morphological alterations in a mouse model of Parkinson’s disease overexpressing mutant A53T alpha-synuclein

Zubelzu M, Bidgood R, Murueta-Goyena A, Ruiz-Ortega J, Lafuente J, Morera-Herreras T.

· 2025-08-01

DOI: 10.1101/2025.07.30.667616

GLP1 secretagogue cinnamaldehyde upregulates GLP1/PI3K/AKT and Nrf2 pathways to exert neuroprotection in a rotenone induced mouse model of Parkinson's disease

Mathur K, Soni R, Yadav R, Patel BD, Shah J.

International Journal of Biological Macromolecules · 2025-08-01

Gut Microbiota-Based Interventions for Parkinson’s Disease: Neuroprotective Mechanisms and Current Perspective

Kumar D, Bishnoi M, Kondepudi KK, Sharma SS.

Probiotics & Antimicro. Prot · 2025-08-01

Targeting ferroptosis and mitophagy with neutrophil-inspired nanozyme for Parkinson's disease therapy

Tian Y, Wang F, Ma J, Huang W, Zhang X, Du C, Wei P, Huang W, Zhu Y, Lin Y.

Journal of Controlled Release · 2025-08-01

Neuroprotective effects of taurine in a rodent model of parkinson’s disease involve modulating astrocyte-mediated inflammation

Moon SM, Kim Ch, Seol J, Yang S, Jung D, Kim CY, Kim CS, Chung KW, Jung YS, Chang SC, Chung HY, Lee J.

Arch. Pharm. Res · 2025-08-01

Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography

Mathas N, Braud E, Galardon E, Larigot L, Etheve-Quelquejeu M, Sari MA, Le Grand B, Blanc EB, Coumoul X, Dairou J.

Biochimie · 2025-08-01

Phenological Growth Stages Based on the BBCH Scale and Thermal Requirements of Spondias dulcis Parkinson

Santos RF, Chagas PC, Moura EA, Moraes Lima ME, Rocha Araújo MC, Chagas EA.

Applied Fruit Science · 2025-08-01

Shared pathogenic mechanisms of Parkinson's disease and ulcerative colitis: α7 nicotinic acetylcholine receptor as a potential therapeutic target

Li Y, Gu Y, Li J, Liu F, Chen H, Hou H, Hu Q.

International Journal of Biological Macromolecules · 2025-08-01

194. RISK OF AGRANULOCYTOSIS AND NEUTROPENIA IN PATIENTS WITH PARKINSON'S DISEASE PSYCHOSIS RECEIVING CLOZAPINE TREATMENT: A SYSTEMATIC REVIEW AND META-ANALYSIS

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The international journal of neuropsychopharmacology · 2025-08-01