SCIENTIFIC HUB

Follow the evidence.

SCIENTIFIC LITERATURE · MED

Hypothalamic abnormalities and Parkinsonism associated with H1N1 influenza infection.

J Neuroinflammation · 2010-08-17

DOI: 10.1186/1742-2094-7-47PMID: 20716355

Open accessResearch Support, Non-U.S. Gov't; research-article; Journal Article; Case ReportsOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

ObjectiveTo describe a case of a young adult with severe H1N1 influenza illness associated with hypothalamic abnormalities and post-influenza parkinsonism.DesignCase report.PatientA 22-year-old woman with H1N1 influenza infection developed encephalopathy followed by diverse hypothalamic dysfunction manifestations, sleeplessness, and persistent parkinsonian features.ResultsCSF analysis, brain imaging and EEG ruled out hypoxic brain injury or other illnesses.ConclusionsA number of viruses have been associated with both acute and chronic parkinsonism. A link between parkinsonism and influenza viruses is somewhat controversial. This is the first reported case of parkinsonism following an H1N1 influenza infection.

Scientific assessment

01

Research question

Assess the question within the original study’s scope.

02

Methods & sample

Check the source article for study design and sample details.

03

Key findings

An editorially approved findings summary is not yet published for this record.

04

Limitations

Generalizability, bias and clinical meaning require separate assessment.

Methods, samples and clinical conclusions are not inferred from bibliographic metadata.