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SCIENTIFIC LITERATURE · MED

Current Pharmacological Management in Juvenile Huntington's Disease.

PLoS Curr · 2012-02-15

DOI: 10.1371/currents.rrn1304PMID: 22474619

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

BackgroundThe clinical presentation of Juvenile Huntington's Disease (JHD) can be very different from adult-onset HD with little evidence to guide symptomatic management.AimTo survey the current use of pharmacological treatments for JHD.MethodsPatients were identified through the HD Association, Hospital Doctors and the European Huntington's Disease Network REGISTRY study.ResultsThe most commonly prescribed agents were anti-psychotics (24/45), anti-depressants (17/45) and anti-parkinsonian medications (15/45). 5 patients were taking more than 8 medications.ConclusionsThe most commonly prescribed group of medication was the anti-psychotic. Many patients were on multiple therapies, highlighting the need to rationalise medications.

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