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SCIENTIFIC LITERATURE · MED

Reduced serum levels of triglyceride, very low density lipoprotein cholesterol and apolipoprotein B in Parkinson's disease patients.

PLoS One · 2013-09-26

DOI: 10.1371/journal.pone.0075743PMID: 24086623

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

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BackgroundPrevious studies have shown a lower incidence of stroke in Parkinson's disease (PD) patients. The role of the lipids and lipoproteins as risk factors for stroke is uncertain in the lower prevalence of stroke in PD patients.ObjectivesTo explore the lipids and lipoproteins serum levels in PD patients.MethodsA retrospective study was performed on 110 PD patients (PD group), 130 controls with non-cerebrovascular neurological diseases (OD group), 140 acute intracerebral hemorrhage patients (ICH group) and 140 acute cerebral infarction patients (CI group). The records about serum levels of lipids and lipoproteins were analyzed.ResultsThere were significant differences for the serum level of triglyceride (F = 5.031, p=0.002), very low density lipoprotein cholesterol (F = 5.313, p=0.001), apolipoprotein B (F = 16.038, pConclusionsThere are reduced serum levels of TG, VLDL-C and apo B in PD patients, which may be related to the decreased prevalence of stroke in PD patients.

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