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ObjectiveTo investigate whether Sjogren's syndrome would have an influence on the development of Parkinson's disease.MethodsA population-based case-control study was conducted. Participants consisted of 7716 subjects with newly diagnosed Parkinson's disease and a population of 75129 matched control subjects between 2000 and 2010. We measured the risk of Parkinson's disease in association with Sjogren's syndrome by using adjusted odds ratios.ResultsA total of 143 Parkinson's disease subjects (1.9%) and 893 control subjects (1.2%) suffered from Sjogren's syndrome (p ConclusionThis study preliminarily proposed that Sjogren's syndrome was significant associated with an increased risk of Parkinson's disease.
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