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ObjectivesThe association of vascular risk factors (VRFs) with incidence of Alzheimer's disease (AD) and vascular dementia (VaD) has been well studied. However, the association between VRFs and non-AD dementia is seldom investigated. In this study, we aim to compare the concurrence of VRFs of Lewy body dementia (LBD) to AD.Materials & methodsWe consecutively enrolled patients with dementia with Lewy bodies (DLB), Parkinson's disease dementia (PDD), and AD, and the prevalence of arterial hypertension, diabetes mellitus, hypercholesterolemia, hyperlipidemia, smoking, and obesity was assessed and compared.ResultsA total of 167 consecutive patients were studied. Among them, 55 had DLB, 34 had PDD, and 78 had AD. History of any VRF among three groups was not significantly different. In addition, the patients with AD had significantly higher systolic pressure (SBP), diastolic pressure (DBP), waist, body mass index (BMI), ac glucose, and HbA1c (all p-value ConclusionsThe VRFs are less associated with LBD than with AD. DLB and PDD showed a similar pattern of the association of VRFs. SBP, BMI, and TG were significantly lower in LBD compared with AD.
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