Brief Psychiatric Screening Questionnaire in Parkinson's Disease.

Research overview

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BackgroundWhile numerous validated questionnaires measuring psychiatric symptoms in Parkinson's disease (PD) are available, a quick multifaceted screening tool is lacking.ObjectiveTo generate the Brief Psychiatric Questionnaire (BPQ) that quickly screens for depression, anxiety, and apathy and to evaluate its content validity against three reference scales.MethodsForty-seven questions were drafted and measured against the Geriatric Depression Scale (GDS), State Trait Anxiety Inventory (Form Y2) (STAI-Y2), and Apathy Evaluation Scale (AES). Data were reduced by principal component analysis and linear regression. Content validity and repeatability were assessed in a second cohort.ResultsData from ninety-five patients were used for BPQ development. Variation explained by the final linear regression models was 52% for GDS (R 2 = 0.521, F(2,94) = 49.97, p R 2 = 0.652, F(4,94) = 42.08, p R 2 = 0.135, F(1,94) = 14.51, p r = 0.464 - 0.733, p p ConclusionsBPQ questions were able to accurately identify patients at risk of depression and anxiety but not apathy. It is brief and multifaceted and can act as a preconsultation tool to prompt further psychiatric assessment.

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